SNC 80

Tocris Bioscience, part of Bio-Techne | Catalog # 0764

COA / SDS

Highly selective non-peptide δ agonist

Key Product Details

Description:	Highly selective non-peptide δ agonist
Chemical Name:	(+)-4-[(αR)-α-((2S,5R)-4-Allyl-2,5-dimethyl-1-piperazinyl)-3-methoxybenzyl]-N,N-diethylbenzamide
Purity:	≥98% (HPLC)
Molecular Weight:	449.64

View Full Technical Details for SNC 80

Technical Data
Citations

Biological Activity for SNC 80

SNC 80 is a highly selective and potent non-peptide δ-opioid agonist, 2000-fold selective over μ-opioid receptors.

Compound Libraries for SNC 80

SNC 80 is also offered as part of the Tocriscreen 2.0 Max. Find out more about compound libraries available from Tocris.

Technical Data for SNC 80

M. Wt	449.64
Formula	C₂₈H₃₉N₃O₂
Storage	Store at RT
Purity	≥98% (HPLC)
CAS Number	156727-74-1
PubChem ID	123924
InChi Key	KQWVAUSXZDRQPZ-UMTXDNHDSA-N
Smiles	[H][C@@](N1C[C@@H](C)N(CC=C)C[C@@H]1C)(C1=CC=C(C=C1)C(=O)N(CC)CC)C1=CC=CC(OC)=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for SNC 80

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
	1eq. HCl	44.96	100 with gentle warming
	DMSO	8.99	20

Preparing Stock Solutions for SNC 80

The following data is based on the product molecular weight 449.64.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	2.22 mL	11.12 mL	22.24 mL
5 mM	0.44 mL	2.22 mL	4.45 mL
10 mM	0.22 mL	1.11 mL	2.22 mL
50 mM	0.04 mL	0.22 mL	0.44 mL

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Reconstitution Calculator

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References for SNC 80

References are publications that support the biological activity of the product.

Calderon Probes for narcotic receptor mediated phenomena. 19. Synthesis of (+)-4-[(αR)-α-((2S,5R)-4-allyl-2,5-dimethyl-1-piperazinyl)-3-methoxybenzyl]-N,N-diethylbenzamide (SNC80): a highly selective nonpeptid J.Med.Chem. 1994 PMID: 8035418
Knapp Structure-activity relationships for SNC80 and related compounds at cloned human delta and mu opioid receptors. J.Pharmacol.Exp.Ther. 1996 PMID: 8667189
Bilsky SNC 80, a selective, nonpeptidic and systemically active opioid δ agonist. J.Pharmacol.Exp.Ther. 1995 PMID: 7714789