SR 11237

Name: SR 11237
Brand: Tocris Bioscience
SKU: 3411

Tocris Bioscience, part of Bio-Techne | Catalog # 3411

Citations (17)

COA / SDS

Pan RXR agonist

Key Product Details

Chemical Name:	4-[2-(5,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1,3-dioxolan-2-yl]-benzoic acid
Purity:	≥98%
Molecular Weight:	380.48 kDa

View Full Technical Details for SR 11237

Technical Data
Citations

Biological Activity for SR 11237

SR 11237 is a pan retinoid X receptor (RXR) agonist that is devoid of any RAR activity.

Technical Data for SR 11237

M. Wt	380.48 kDa
Formula	C₂₄H₂₈O₄
Storage	Store at -20°C
Purity	≥98%
CAS Number	146670-40-8

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for SR 11237

Solubility

Soluble Soluble to 100 mM in DMSO

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References for SR 11237

References are publications that support the biological activity of the product.

Whelan J, Wang L, Chen J, Metts M, Nasser T, McGoldrick L, Bridges L Retinoids induce integrin-independent lymphocyte adhesion through RAR-alpha nuclear receptor activity. Biochem Biophys Res Commun, 2014;454(4):537-542. 2014 PMID: 25450689
Chiba et al. Distinct retinoid X receptor-retinoic acid receptor heterodimers are differentially involved in the control of expression of retinoid target genes in F9 embryonal carcinoma cells. Mol.Cell.Biol., 1997;17:3013 PMID: 9154799
Benoit et al. RAR-independent RXR signaling induces t(15;17) leukemia cell maturation. EMBO J., 1999;18:7011 PMID: 10601023
Zhou et al. Retinoid X receptor agonists inhibit phorbol-12-myristate-13-acetate (PMA)-induced differentiation of monocytic THP-1 cells into macrophages. Mol.Cell.Biochem., 2010;335:283 PMID: 19784811