T3

Name: T3
Brand: Tocris Bioscience
SKU: 6666

Tocris Bioscience, part of Bio-Techne | Catalog # 6666

Citations (2)

COA / SDS

Thyroid hormone; also promotes differentiation of oligodendroglial precursor cells

Key Product Details

Chemical Name:	O-(4-Hydroxy-3-iodophenyl-3,5-diiodo-L-tyrosine
Purity:	≥98%

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Technical Data
Citations

Biological Activity for T3

T3 is a thyroid hormone. Promotes differentiation of oligodendroglial precursor cells in neonatal rats and promotes maturation of hiPSC-derived cardiomyocytes. Also specifies cone cell subtype in retinal cell differentiation protocols. T3 is used in protocols to generate cortical spheroids from hPSCs.

T3 synthesized to Ancillary Material Grade also available.

For more information about how T3 may be used, see our protocol: Generation of β cells from hPSCs

Technical Data for T3

Formula	C₁₅H₁₂I₃NO₄
Storage	Store at -20°C
Purity	≥98%
CAS Number	6893-02-3

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for T3

Solubility

Soluble Soluble to 50 mM in DMSO

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References for T3

References are publications that support the biological activity of the product.

Madhavan et al. Induction of myelinating oligodendrocytes in human cortical spheroids. Nat.Methods., 2018;15:700 PMID: 30046099
Marta et al. Sustained neonatal hyperthyroidism in the rat affects myelination in the central nervous system. J.Neurosci.Res., 1998;53:251 PMID: 9671982
Yang et al. Tri-iodo-L-thyronine promotes the maturation of human cardiomyocytes-derived from induced pluripotent stem cells. J.Mol.CellCardiol., 2014;72:296 PMID: 24735830
Eldred et al. Thyroid hormone signaling specifies cone subtypes in human retinal organoids. Science, 2018;362:eaau6348 PMID: 30309916

T3

Tocris Bioscience, part of Bio-Techne | Catalog # 6666

Key Product Details

Biological Activity for T3

Technical Data for T3

Solubility for T3

Dilution Calculator

Reconstitution Calculator

References for T3

Product Documents for T3

COA

Certificate of Analysis

SDS

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