Triacsin C

Name: Triacsin C
Brand: Tocris Bioscience
SKU: 2472

Tocris Bioscience, part of Bio-Techne | Catalog # 2472

Citations (9)

COA / SDS

Inhibitor of acyl-CoA synthetase

Key Product Details

Description:	Inhibitor of acyl-CoA synthetase
Chemical Name:	(2E,4E,7E)-2,4,7-Undecatrienal nitrosohydrazone
Purity:	≥95% (HPLC)
Molecular Weight:	207.27

View Full Technical Details for Triacsin C

Technical Data
Citations

Biological Activity for Triacsin C

Triacsin C is an inhibitor of acyl-CoA synthetase. Inhibits lipid synthesis and cell proliferation in Raji lymphoma cells. Induces apoptosis in cancer cell lines and inhibits human lung cancer cell xenograft tumor growth in mice.

Technical Data for Triacsin C

M. Wt	207.27
Formula	C₁₁H₁₇N₃O
Storage	Store at -20°C
Purity	≥95% (HPLC)
CAS Number	76896-80-5
PubChem ID	9576787
InChi Key	NKTGCVUIESDXPU-YLEPRARLSA-N
Smiles	O=NN/N=C/C=C/C=C/C/C=C/CCC

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for Triacsin C

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
Solubility	DMSO	5

Preparing Stock Solutions for Triacsin C

The following data is based on the product molecular weight 207.27.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.25 mM	19.30 mL	96.49 mL	192.98 mL
1.25 mM	3.86 mL	19.30 mL	38.60 mL
2.5 mM	1.93 mL	9.65 mL	19.30 mL
12.5 mM	0.39 mL	1.93 mL	3.86 mL

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References for Triacsin C

References are publications that support the biological activity of the product.

Mashima p53-defective tumors with a functional apoptosome-mediated pathway: a new therapeutic target. J.Natl.Cancer.Inst. 2005 PMID: 15900046
Tomoda Evidence for an essential role of long chain acyl-CoA synthetase in animal cell proliferation. Inhibition of long chain acyl-CoA synthetase by triacsins caused inhibition of Raji cell proliferation. J.Biol.Chem. 1991 PMID: 1999415