WDR5 0103

Name: WDR5 0103
Brand: Tocris Bioscience
SKU: 5323

Tocris Bioscience, part of Bio-Techne | Catalog # 5323

(1)

Citations (4)

COA / SDS

WDR5 antagonist

Key Product Details

Chemical Name:	3-[(3-Methoxybenzoyl)amino]-4-(4-methyl-1-piperazinyl)benzoic acid methyl ester
Purity:	≥99%

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Technical Data
Citations / Reviews (1)

Biological Activity for WDR5 0103

WDR5 0103 is a WD repeat-containing protein 5 (WDR5) antagonist (K_d = 450 nM). Disrupts WDR5 interaction with MLL and inhibits MLL core complex methyltransferase activity in vitro. Has no effect on a panel of seven other methyltransferases, including SETD7.

Technical Data for WDR5 0103

Formula	C₂₁H₂₅N₃O₄
Storage	Store at +4°C
Purity	≥99%
CAS Number	890190-22-4

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for WDR5 0103

Solubility

Soluble Soluble to 100 mM in DMSO and to 50 mM in ethanol

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References for WDR5 0103

References are publications that support the biological activity of the product.

Senisterra et al. Small-molecule inhibition of MLL activity by disruption of its interaction with WDR5. Biochem.J., 2013;449:151 PMID: 22989411

WDR5 0103

Tocris Bioscience, part of Bio-Techne | Catalog # 5323

Key Product Details

Biological Activity for WDR5 0103

Technical Data for WDR5 0103

Solubility for WDR5 0103

Dilution Calculator

Reconstitution Calculator

References for WDR5 0103

Product Documents for WDR5 0103

COA

Certificate of Analysis

SDS

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