XCC

Tocris Bioscience, part of Bio-Techne | Catalog # 4220

COA / SDS

Adenosine receptor antagonist

Key Product Details

Description:	Adenosine receptor antagonist
Chemical Name:	2-[4-(2,3,6,7-Tetrahydro-2,6-dioxo-1,3-dipropyl-1H-purin-8-yl)phenoxy]-acetic acid
Purity:	≥98% (HPLC)
Molecular Weight:	386.4

View Full Technical Details for XCC

Technical Data
Citations

Biological Activity for XCC

XCC is an adenosine receptor antagonist (K_i values are 42, 68 and 1130 nM for A₁, A_2B and A_2A receptors).

Technical Data for XCC

M. Wt	386.4
Formula	C₁₉H₂₂N₄O₅
Storage	Desiccate at RT
Purity	≥98% (HPLC)
CAS Number	96865-83-7
PubChem ID	126079
InChi Key	QTMMGCYGCFXBFI-UHFFFAOYSA-N
Smiles	O=C1N(CCC)C(C(NC(C3=CC=C(OCC(O)=O)C=C3)=N2)=C2N1CCC)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for XCC

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
Solubility	DMSO	19.32	50

Preparing Stock Solutions for XCC

The following data is based on the product molecular weight 386.4.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.5 mM	5.18 mL	25.88 mL	51.76 mL
2.5 mM	1.04 mL	5.18 mL	10.35 mL
5 mM	0.52 mL	2.59 mL	5.18 mL
25 mM	0.10 mL	0.52 mL	1.04 mL

Molarity Calculator

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Reconstitution Calculator

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References for XCC

References are publications that support the biological activity of the product.

Sebastiao The inhibitory adenosine receptor at the neuromuscular junction and hippocampus of the rat: antagonism by 1,3,8-substituted xanthines. Br.J.Pharmacol. 1990 PMID: 2257444
Thummler and Dunwiddie Adenosine receptor antagonists induce persistent bursting in the rat hippocampal CA3 region via an NMDA receptor-dependent mechanism. J.Neurophysiol. 2000 PMID: 10758091
Jarvis Autoradiographic characterization of high-affinity adenosine A₂ receptors in the rat brain. Brain Res. 1989 PMID: 2713675

XCC