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Product Overview​

The RNAscope™ VS Universal HRP/AP assays are RNA in situ hybridization assays based on ACD’s patented signal amplification and background suppression technology automated on DISCOVERY ULTRA instrument, an automated IHC/ISH slide staining platform from Roche Tissue Diagnostics. The assay uses a proprietary method of in situ hybridization (ISH) to visualize single RNA molecules per cell in a multitude of sample types mounted on slides. RNAscope Assays do not require the RNA-free environment used for traditional ISH.​

The RNAscope VS Universal HRP assay is a very robust assay giving reliable results that are ideal for archiving when used with the mRNA DAB Detection kit from Roche Tissue Diagnostics.  It is the standard in molecular pathology diagnostics usable for a wide source of samples and the results are visible under any standard bright field microscope. ​

​Learn more about the applications of powerful ISH–IHC multiplexing, which is enabling molecular pathology globally.

Product Offerings

RNAscope automated assay on Roche Discover Ultra image of human ovarian cancer

RNAscope™ VS HRP/AP assay (automated)

The RNAscope VS Universal HRP/AP assays are RNA in situ hybridization assays based on ACD’s patented signal amplification and background suppression technology automated on DISCOVERY ULTRA instrument, an automated IHC-ISH slide staining platform from Roche Tissue Diagnostics.

 

Automated RNAscope assay on Roche Discover Ultra image showing mouse brain tissue

RNAscope™ VS Duplex assay (automated)

RNAscope VS Duplex Kit is designed for simultaneous in situ detection of two RNA species. To distinguish between the two targets, individual probes are used in probe channels 1 (C1) and Channel 2 (C2).

Automated RNAscope assay on Roche Discovery Ultra image showing lung tissue

BaseScope™ VS assay (automated)

The BaseScope VS assay leverages the same platform as proven and established within the RNAscope™ technology but expands the detection capabilities, enabling the detection of short RNA target sequences and exon junctions in cells and tissues with morphological context, providing new data dimensions and unique insight into biological mechanisms.