5-HT2A Products
5-HT2A encodes one of the receptors for serotonin, a neurotransmitter with many roles. Mutations in 5-HT2A are associated with susceptibility to schizophrenia and obsessive-compulsive disorder, and are also associated with response to the antidepressant citalopram in patients with major depressive disorder (MDD). MDD patients who also have a mutation in intron 2 of 5-HT2A show a significantly reduced response to citalopram as this antidepressant downregulates expression of this gene.
69 results for "5-HT2A" in Products
69 results for "5-HT2A" in Products
5-HT2A Products
5-HT2A encodes one of the receptors for serotonin, a neurotransmitter with many roles. Mutations in 5-HT2A are associated with susceptibility to schizophrenia and obsessive-compulsive disorder, and are also associated with response to the antidepressant citalopram in patients with major depressive disorder (MDD). MDD patients who also have a mutation in intron 2 of 5-HT2A show a significantly reduced response to citalopram as this antidepressant downregulates expression of this gene.
Endogenous 5-HT receptor agonist
Alternate Names: | 5-Hydroxytryptamine,5-HT |
Chemical Name: | 3-(2-Aminoethyl)-1H-indol-5-ol hydrochloride |
Purity: | ≥98% (HPLC) |
Details: | Mouse IgG1 Monoclonal Clone #1055217 |
Applications: | WB, Flow, ICC |
Dopamine antagonist with some D4 selectivity; also 5-HT2A/2C antagonist
Chemical Name: | 8-Chloro-11-(4-methyl-1-piperazinyl)-5H-dibenzo[b,e][1,4]diazepine |
Purity: | ≥99% (HPLC) |
High affinity and selective 5-HT2A agonist
Alternate Names: | 25CN-NBOH |
Chemical Name: | 4-[2-[[(2-Hydroxyphenyl)methyl]amino]ethyl]-2,5-dimethoxybenzonitrile hydrochloride |
Purity: | ≥98% (HPLC) |
Reactivity: | Human |
Details: | Mouse IgG1 Monoclonal Clone #1055220 |
Applications: | Flow, ICC |
5-HT2A antagonist
Chemical Name: | α-Phenyl-1-(2-phenylethyl)-4-piperidinemethanol |
Purity: | ≥99% (HPLC) |
Potent and selective 5-HT2A antagonist
Alternate Names: | Volinanserin |
Chemical Name: | (R)-(+)-α-(2,3-Dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperinemethanol |
Purity: | ≥98% (HPLC) |
5-HT2 antagonist; also D2 antagonist; atypical antipsychotic
Alternate Names: | ICI 204,636 |
Chemical Name: | 2-[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]ethanol hemifumarate |
Purity: | ≥99% (HPLC) |
5-HT2A and α1 adrenoceptor antagonist; also enhances neural differentiation; antidepressant and neuroprotectant
Chemical Name: | 2-[3-[4-(3-Chlorophenyl)-1-piperazinyl]propyl]-1,2,4-triazolo[4,3-a]pyridin-3(2H)-one hydrochloride |
Purity: | ≥99% (HPLC) |
Selective 5-HT2A antagonist. Also antagonist at 5-HT1D
Alternate Names: | R 41 468 |
Chemical Name: | 3-[2-[4-(4-Fluorobenzoyl)-1-piperidinyl]ethyl]-2,4[1H,3H]-quinazolinedione tartrate |
Purity: | ≥97% (HPLC) |
Potent, selective 5-HT2A antagonist
Chemical Name: | (2R,4R)-5-[2-[2-[2-(3-Methoxyphenyl)ethyl]phenoxy]ethyl]-1-methyl-3-pyrrolidinol hydrochloride |
Purity: | ≥99% (HPLC) |
High affinity and potent 5-HT2A agonist
Chemical Name: | (4-Bromo-3,6-dimethoxybenzocyclobuten-1-yl)methylamine hydrobromide |
Purity: | ≥99% (HPLC) |
Selective 5-HT2A antagonist
Chemical Name: | 7-[[4-[2-(4-Fluorophenyl)ethyl]-1-piperazinyl]carbonyl]-1H-indole-3-carbonitrile hydrochloride |
Purity: | ≥98% (HPLC) |
Reactivity: | Human |
Details: | Goat IgG Polyclonal |
Applications: | IHC, ELISA, ICC/IF, Flow |
Reactivity: | Human |
Details: | Mouse IgG1 Monoclonal Clone #1055220 |
Applications: | Flow |
Reactivity: | Human |
Details: | Mouse IgG1 Monoclonal Clone #1055220 |
Applications: | Flow |
Reactivity: | Human |
Details: | Mouse IgG1 Monoclonal Clone #1055220 |
Applications: | Flow |
Reactivity: | Human |
Details: | Mouse IgG1 Monoclonal Clone #1055220 |
Applications: | Flow |
Selective 5-HT2A antagonist
Chemical Name: | 4-(4-Fluorobenzoyl)-1-(4-phenylbutyl)piperidine oxalate |
Purity: | ≥99% (HPLC) |
5-HT2A and 5-HT2C antagonist; also D2-like partial agonist
Alternate Names: | CU-32-085 |
Chemical Name: | N'-[(8-α1,6-dimethylergolin-8-yl]-N,N-dimethylsulfamide hydrochloride |
Purity: | ≥99% (HPLC) |
5-HT2A antagonist; also D2 antagonist; atypical antipsychotic
Alternate Names: | 9-Hydroxyrisperidone,9-OH-risperidone |
Chemical Name: | 3-[2-[4-(6-Fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl]-6,7,8,9-tetrahydro-9-hydroxy-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one |
Purity: | ≥98% (HPLC) |
Potent and selective 5-HT2A antagonist
Alternate Names: | SR-46349 hemifumarate,SR-46349B |
Chemical Name: | (1Z,2E)-1-(2-Fluorophenyl)-3-(4-hydroxyphenyl)-2-propen-1-one O-[2-(dimethylamino)ethyl]oxime hemifumarate |
Purity: | ≥98% (HPLC) |
5-HT2A antagonist; also D2 antagonist; atypical antipsychotic
Alternate Names: | R 64 766 |
Chemical Name: | 3-[2-[4-(6-Fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl]-6,7,8,9-tetrahydro-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one |
Purity: | ≥99% (HPLC) |
5-HT2A receptor antagonist
Chemical Name: | 3-[2-[4-(4-Fluorobenzoyl)-1-piperidinyl]ethyl]-2,3-dihydro-2-thioxo-4(1H)-quinazolinone hydrochloride |
Purity: | ≥98% (HPLC) |