B7-2/CD86 Products
B7-2/CD86 and the related B7-1/CD80 are transmembrane cell surface molecules that play important roles in immune activation and the maintenance of immune tolerance. B7-2 is highly expressed on activated antigen presenting cells and vascular endothelial cells. It binds to CD28 on T cells to enhance T cell activation. It additionally binds CTLA-4 which inhibits the T cell response and supports regulatory T cell function. The relative participation of B7-1 and B7-2 in T cell co-stimulation can alter the Th1/Th2 bias of the immune response. Both B7-1 and B7-2 serve as cellular receptors for B species adenoviruses.
268 results for "B7-2/CD86" in Products
268 results for "B7-2/CD86" in Products
B7-2/CD86 Products
B7-2/CD86 and the related B7-1/CD80 are transmembrane cell surface molecules that play important roles in immune activation and the maintenance of immune tolerance. B7-2 is highly expressed on activated antigen presenting cells and vascular endothelial cells. It binds to CD28 on T cells to enhance T cell activation. It additionally binds CTLA-4 which inhibits the T cell response and supports regulatory T cell function. The relative participation of B7-1 and B7-2 in T cell co-stimulation can alter the Th1/Th2 bias of the immune response. Both B7-1 and B7-2 serve as cellular receptors for B species adenoviruses.
Clone BU63 was used by HLDA to establish CD designation.
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG1 kappa Monoclonal Clone #BU63 |
| Applications: | IHC, WB, ICC/IF, Flow, B/N, +1 More |
![Knockout Validated: B7-2/CD86 Antibody (BU63) [NBP2-25208]](https://resources.bio-techne.com/images/products/B7-2-CD86-Antibody-BU63-Knockout-Validated-NBP2-25208-img0005.jpg "Knockout Validated: B7-2/CD86 Antibody (BU63) [NBP2-25208]")
| Source: | NS0 |
| Accession #: | AAB03814 |
| Applications: | BA |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IHC, KO, Neut |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #37301 |
| Applications: | WB, Flow, CyTOF-ready, KO, Neut |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #37301 |
| Applications: | Flow |
| Reactivity: | Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, Neut |
Recombinant Monoclonal Antibody.
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #SJ20-00 |
| Applications: | IHC, WB, ICC/IF, IP |
| Reactivity: | Mouse |
| Details: | Rat IgG2 Monoclonal Clone #AP-MAB0803 |
| Applications: | IHC, ICC/IF, Flow, CyTOF-ready |
![Immunohistochemistry-Paraffin: B7-2/CD86 Antibody (AP-MAB0803) - Azide and BSA Free [NBP2-12182]](https://resources.bio-techne.com/images/products/CD86-Antibody-AP-MAB0803-Immunohistochemistry-Paraffin-NBP2-12182-img0001.jpg "Immunohistochemistry-Paraffin: B7-2/CD86 Antibody (AP-MAB0803) - Azide and BSA Free [NBP2-12182]")
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #37301 |
| Applications: | Flow |
| Reactivity: | Rat |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, Flow, IHC, CyTOF-ready |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #37301 |
| Applications: | Flow |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG1 kappa Monoclonal Clone #C86/1146 |
| Applications: | IHC, WB, ICC/IF, Flow, KO |
![Knockout Validated: B7-2/CD86 Antibody (C86/1146) [NBP2-44514]](https://resources.bio-techne.com/images/products/B7-2-CD86-Antibody-C86-1146-Knockout-Validated-NBP2-44514-img0006.jpg "Knockout Validated: B7-2/CD86 Antibody (C86/1146) [NBP2-44514]")
| Reactivity: | Mouse |
| Details: | Rat IgG2a Monoclonal Clone #133412 |
| Applications: | IHC |
| Reactivity: | Cynomolgus Monkey |
| Details: | Mouse IgG1 Monoclonal Clone #1029808 |
| Applications: | WB, IHC, KO |
| Reactivity: | Mouse |
| Details: | Rat IgG2a Monoclonal Clone #GL1 |
| Applications: | WB, Flow, CyTOF-ready, Neut |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #37301 |
| Applications: | Flow |
Biotinylated
| Source: | CHO |
| Accession #: | AAH40261.1 |
| Applications: | BA, BA |
Fc Chimera
| Source: | CHO |
| Accession #: | AAB03814.1 |
| Applications: | BA |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG1 kappa Monoclonal Clone #SPM600 |
| Applications: | IHC, ICC/IF |
![Immunocytochemistry/ Immunofluorescence: B7-2/CD86 Antibody (SPM600) [NBP2-44515]](https://resources.bio-techne.com/images/products/B7-2-CD86-Antibody-SPM600-Immunocytochemistry-Immunofluorescence-NBP2-44515-img0002.jpg "Immunocytochemistry/ Immunofluorescence: B7-2/CD86 Antibody (SPM600) [NBP2-44515]")
| Source: | HEK293 |
| Accession #: | XP_005548057 |
| Applications: | BA |
| Reactivity: | Rat |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IHC |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #1036431 |
| Applications: | IHC |
Fc Chimera
| Source: | CHO |
| Accession #: | AAB03814.1 |
| Applications: | BA |
| Assay Range: | 46.9 - 3,000 pg/mL |
| Applications: | ELISA |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |