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c-Myc Products

Human c-Myc is a 439 amino acid transcription factor with a bHLH/LZ (basic Helix-Loop-Helix, Leucine Zipper) domain. c-Myc DNA-binding and transcription function is achieved upon heterodimerization with its partner Max. c-Myc is often over-expressed and mutated in hematopoietic tumors. Mutations in c-Myc frequently result in truncations that remove the transactivation region or in the bHLH/LZ domain required for association with Max and DNA.

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3 results for "c-Myc" in Products

3 results for "c-Myc" in Products

c-Myc Products

Human c-Myc is a 439 amino acid transcription factor with a bHLH/LZ (basic Helix-Loop-Helix, Leucine Zipper) domain. c-Myc DNA-binding and transcription function is achieved upon heterodimerization with its partner Max. c-Myc is often over-expressed and mutated in hematopoietic tumors. Mutations in c-Myc frequently result in truncations that remove the transactivation region or in the bHLH/LZ domain required for association with Max and DNA.

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Applications: IHC, WB, ELISA, ICC/IF, IP, B/N
Reactivity: Human, Mouse, Non-species specific
Applications: ICFlow
Reactivity: Human
Applications: WB, ELISA, ICC/IF, IP, IHC (-)
Reactivity: Human, Mouse, Non-species specific
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