Caspase-3 Products
Caspase-3 is a widely expressed dimeric peptidase that is the major executioner caspase, the primary downstream mediator of apoptotic-associated proteolysis. Caspase-3 cleaves multiple substrates including PARP, proIL-16, PKC-gamma and -delta, proCaspases-6, -7, and -9, and beta-Catenin.
Normally, it is an inactive, exclusively cytosolic homodimer. During apoptosis, however, proCaspase-3 is activated by cleavage into p20 and p12 subunits, and the p20 subunit is trimmed to yield a p17 subunit. Active Caspase-3 contains two p17 and two p12 subunits.
Products:
3 results for "Caspase-3" in Products
3 results for "Caspase-3" in Products
Caspase-3 Products
Caspase-3 is a widely expressed dimeric peptidase that is the major executioner caspase, the primary downstream mediator of apoptotic-associated proteolysis. Caspase-3 cleaves multiple substrates including PARP, proIL-16, PKC-gamma and -delta, proCaspases-6, -7, and -9, and beta-Catenin.
Normally, it is an inactive, exclusively cytosolic homodimer. During apoptosis, however, proCaspase-3 is activated by cleavage into p20 and p12 subunits, and the p20 subunit is trimmed to yield a p17 subunit. Active Caspase-3 contains two p17 and two p12 subunits.
Products:
| Reactivity: | Human, Mouse, Rat, Porcine, Rabbit, +5 More |
| Details: | Mouse IgG1 kappa Monoclonal Clone #31A1067 |
| Applications: | IHC, WB, ICC/IF, Flow, CyTOF-ready, +6 More |
| Reactivity: | Human, Mouse, Rat, Canine, Bovine, +4 More |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF |
![Immunohistochemistry-Paraffin: Caspase-3 Antibody [NB600-1235]](https://resources.bio-techne.com/images/products/Caspase-3-Antibody-Immunohistochemistry-Paraffin-NB600-1235-img0003.jpg "Immunohistochemistry-Paraffin: Caspase-3 Antibody [NB600-1235]")
| Reactivity: | Human, Mouse, Rat, Porcine, Rabbit, +3 More |
| Details: | Mouse IgG1 kappa Monoclonal Clone #31A1067 |
| Applications: | IHC, WB, ICC/IF, Flow, CyTOF-ready, +4 More |
