Caspase-9 Products
Caspase-9, also known as APAF-3, Mch6, and ICE-LAP6, is a 35-37 kDa member of the peptidase C14A family of enzymes. Caspase-9 is an initiator caspase that is part of the intrinsic apoptosis pathway. It is widely expressed and is particularly important during development. Following the mitochondrial disruption, Cytochrome c is released from mitochondria and interacts with APAF-1, resulting in Pro-Caspase-9 dimerization. The act of dimerization activates Pro-Caspase-9, leading to its autocleavage into p35 and p12 subunits or to its activation of Caspase-3. Activated Caspase-3 can also act on Pro-Caspase-9, generating a 37 kDa subunit and a 10 kDa subunit.
Products:
90 results for "Caspase-9" in Products
90 results for "Caspase-9" in Products
Caspase-9 Products
Caspase-9, also known as APAF-3, Mch6, and ICE-LAP6, is a 35-37 kDa member of the peptidase C14A family of enzymes. Caspase-9 is an initiator caspase that is part of the intrinsic apoptosis pathway. It is widely expressed and is particularly important during development. Following the mitochondrial disruption, Cytochrome c is released from mitochondria and interacts with APAF-1, resulting in Pro-Caspase-9 dimerization. The act of dimerization activates Pro-Caspase-9, leading to its autocleavage into p35 and p12 subunits or to its activation of Caspase-3. Activated Caspase-3 can also act on Pro-Caspase-9, generating a 37 kDa subunit and a 10 kDa subunit.
Products:
| Reactivity: | Human, Mouse, Rat, Canine, Gerbil |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF, Flow, IP |
![Immunohistochemistry: Caspase-9 Antibody [NB100-56118]](https://resources.bio-techne.com/images/products/Caspase-9-Antibody-Immunohistochemistry-NB100-56118-img0014.jpg "Immunohistochemistry: Caspase-9 Antibody [NB100-56118]")
| Reactivity: | Human |
| Details: | Mouse IgG1 kappa Monoclonal Clone #LAP6 96-2-22 |
| Applications: | IHC, WB, ICC/IF, Simple Western, KD |
![Western Blot: Caspase-9 Antibody (LAP6 96-2-22)BSA Free [NB500-209]](https://resources.bio-techne.com/images/products/Caspase-9-Antibody-LAP6-96-2-22-Western-Blot-NB500-209-img0006.jpg "Western Blot: Caspase-9 Antibody (LAP6 96-2-22)BSA Free [NB500-209]")
| Reactivity: | Human, Mouse, Rat, Canine |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF, IP, Simple Western |
![Western Blot: Caspase-9 Antibody [NB100-56119]](https://resources.bio-techne.com/images/products/Caspase-9-Antibody-Western-Blot-NB100-56119-img0003.jpg "Western Blot: Caspase-9 Antibody [NB100-56119]")
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #LAP6 |
| Applications: | WB, Simple Western, IHC |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
Potent pan-caspase inhibitor
| Chemical Name: | N-[2-(1,1-Dimethylethyl)phenyl]-2-oxoglycyl-N-[(1S)-1-(carboxymethyl)-2-oxo-3-(2,3,5,6-tetrafluorophenoxy)propyl]-L-alaninamide |
| Purity: | ≥98% (HPLC) |
Recombinant Monoclonal Antibody.
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #SZ29-01 |
| Applications: | IHC, WB, ICC/IF, IP |
![Western Blot: Caspase-9 Antibody (SZ29-01)(Pro and Active) [NBP2-67362]](https://resources.bio-techne.com/images/products/Caspase-9-Antibody-SZ29-01-Pro-and-Active-Western-Blot-NBP2-67362-img0008.jpg "Western Blot: Caspase-9 Antibody (SZ29-01)(Pro and Active) [NBP2-67362]")
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ELISA, ICC/IF, IP |
![Western Blot: Caspase-9 AntibodyBSA Free [NBP1-76961]](https://resources.bio-techne.com/images/products/Caspase-9-Antibody-Western-Blot-NBP1-76961-img0015.jpg "Western Blot: Caspase-9 AntibodyBSA Free [NBP1-76961]")
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, IP |
![Western Blot: Caspase-9 [p Ser196] Antibody [NB100-56122]](https://resources.bio-techne.com/images/products/Caspase-9-[p-Ser196]-Antibody-Western-Blot-NB100-56122-img0004.jpg "Western Blot: Caspase-9 [p Ser196] Antibody [NB100-56122]")
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF |
![Western Blot: Caspase-9 Antibody [NBP1-90142]](https://resources.bio-techne.com/images/products/Caspase-9-Antibody-Western-Blot-NBP1-90142-img0010.jpg "Western Blot: Caspase-9 Antibody [NBP1-90142]")
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, IP |
![Western Blot: Caspase-9 Antibody [NB100-56121]](https://resources.bio-techne.com/images/products/Caspase-9-Antibody-Western-Blot-NB100-56121-img0005.jpg "Western Blot: Caspase-9 Antibody [NB100-56121]")
| Reactivity: | Human, Primate |
| Details: | Mouse IgG1 Monoclonal Clone #2-22 |
| Applications: | IHC, WB, IP |
![Western Blot: Caspase-9 Antibody (2-22) [NBP1-19231]](https://resources.bio-techne.com/images/products/Caspase-9-Antibody-2-22-Western-Blot-NBP1-19231-img0012.jpg "Western Blot: Caspase-9 Antibody (2-22) [NBP1-19231]")
Promotes apoptosome formation and activates caspase-9/caspase-3 pathway. Selectively induces tumor cell apoptosis
| Chemical Name: | 1-[(3,4-Dichlorophenyl)methyl]-1H-indole-2,3-dione |
| Purity: | ≥99% (HPLC) |
Recombinant Monoclonal Antibody
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #9M6N2 |
| Applications: | WB, ELISA, ICC/IF |
![Western Blot: Caspase-9 Antibody (9M6N2) [NBP3-15590]](https://resources.bio-techne.com/images/products/Caspase-9-Antibody-4E5G9-Western-Blot-NBP3-15590-img0005.jpg "Western Blot: Caspase-9 Antibody (9M6N2) [NBP3-15590]")
| Applications: | ELISA |
| Applications: | ELISA |
![ELISA: Human Caspase-9 ELISA Kit (Colorimetric) [NBP1-83734]](https://resources.bio-techne.com/images/products/Caspase-9-ELISA-Kit-ELISA-NBP1-83734-img0001.jpg "ELISA: Human Caspase-9 ELISA Kit (Colorimetric) [NBP1-83734]")
Recombinant monoclonal antibody expressed in HEK293F cells
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #8G5 |
| Applications: | ELISA, ICC/IF, Flow |
Recombinant monoclonal antibody expressed in HEK293F cells
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #2D5 |
| Applications: | WB, ELISA, ICC/IF, Flow |
| Applications: | AC |
| Applications: | AC |
Recombinant Monoclonal Antibody
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Monoclonal Clone #S09-4C4 |
| Applications: | WB |
![Western Blot: Caspase-9 Antibody (S09-4C4) [NBP3-19935]](https://resources.bio-techne.com/images/products/Caspase-9-Antibody-S09-4C4-Western-Blot-NBP3-19935-img0001.jpg "Western Blot: Caspase-9 Antibody (S09-4C4) [NBP3-19935]")
| Applications: | Bioactivity, PAGE |
| Applications: | ELISA |
