CCL4/MIP-1 beta Products
CCL4/MIP-1 beta is a beta chemokine that is secreted at sites of inflammation by activated leukocytes, lymphocytes, vascular endothelial cells, and pulmonary smooth muscle cells. It attracts a variety of immune cells to sites of microbial infection as well as to other pathologic inflammation such as allergic asthma and ischemic myocardium. CCL4 is secreted from activated monocytes as a heterodimer with CCL3/MIP-1 alpha. It signals through CCR5, and an N-terminally trimmed form additionally interacts with CCR1 and CCR2. In humans, the ability of CCL4 to bind CCR5 inhibits the cellular entry of M-tropic HIV-1 which utilizes CCR5 as a coreceptor.
63 results for "CCL4/MIP-1 beta" in Products
63 results for "CCL4/MIP-1 beta" in Products
CCL4/MIP-1 beta Products
CCL4/MIP-1 beta is a beta chemokine that is secreted at sites of inflammation by activated leukocytes, lymphocytes, vascular endothelial cells, and pulmonary smooth muscle cells. It attracts a variety of immune cells to sites of microbial infection as well as to other pathologic inflammation such as allergic asthma and ischemic myocardium. CCL4 is secreted from activated monocytes as a heterodimer with CCL3/MIP-1 alpha. It signals through CCR5, and an N-terminally trimmed form additionally interacts with CCR1 and CCR2. In humans, the ability of CCL4 to bind CCR5 inhibits the cellular entry of M-tropic HIV-1 which utilizes CCR5 as a coreceptor.
| Assay Range: | 15.6 - 1,000 pg/mL |
| Applications: | ELISA |
| Sensitivity: |
4 pg/mL (Cell Culture Supernates) 11 pg/mL (Serum, EDTA Plasma, Heparin Plasma, Citrate Plasma) |
| Applications: | ELISA |
| Assay Range: |
15.6 - 1,000 pg/mL (Cell Culture Supernates) 31.2 - 2,000 pg/mL (Serum, EDTA Plasma, Heparin Plasma, Citrate Plasma) |
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #24006 |
| Applications: | WB, CyTOF-ready, ICFlow, Neut |
| Sensitivity: | 3 pg/mL |
| Applications: | ELISA |
| Assay Range: | 7.8 - 500 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma) |
| Source: | E. coli |
| Accession #: | P13236.1 |
| Applications: | BA |
