Checkpoint Control Kinase Inhibitors Products
16 results for "Checkpoint Control Kinase Inhibitors" in Products
16 results for "Checkpoint Control Kinase Inhibitors" in Products
Checkpoint Control Kinase Inhibitors Products
Potent and selective ATM kinase inhibitor
| Chemical Name: | 2-(4-Morpholinyl)-6-(1-thianthrenyl)-4H-pyran-4-one |
| Purity: | ≥98% (HPLC) |
Potent and selective BUB1 kinase inhibitor
| Chemical Name: | 2-[3,5-Difluoro-4-[[3-[5-methoxy-4-[(3-methoxy-4-pyridinyl)amino]-2-pyrimidinyl]-1H-indazol-1-yl]methyl]phenoxy]ethanol |
| Purity: | ≥98% (HPLC) |
Potent Src inhibitor; also inhibits FGFR1, PDGFRβ and Wee1
| Chemical Name: | 6-(2,6-Dichlorophenyl)-2-[[4-[2-(diethylamino)ethoxy]phenyl]amino]-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one dihydrochloride |
| Purity: | ≥99% (HPLC) |
Potent and selective Mps1 kinase inhibitor
| Chemical Name: | 9-Cyclopentyl-2-[[2-methoxy-4-[(1-methylpiperidin-4-yl)oxy]-phenyl]amino]-7-methyl-7,9-dihydro-8H-purin-8-one |
| Purity: | ≥99% (HPLC) |
Selective Mps1 kinase inhibitor
| Chemical Name: | 1-[3-Methoxy-4-[[4-[[2-[(1-methylethyl)sulfonyl]phenyl]amino]-1H-pyrrolo[2,3-b]pyridin-6-yl]amino]phenyl]-4-piperidinol dihydrochloride |
| Purity: | ≥98% (HPLC) |
Inhibitor of PI 3-kinase, mTOR and DNA-PK
| Chemical Name: | 3-[4-(4-Morpholinylpyrido[3',2':4,5]furo[3,2-d]pyrimidin-2-yl]phenol hydrochloride |
| Purity: | ≥98% (HPLC) |
Potent and selective DNA-PK inhibitor
| Alternate Names: | KU 57788 |
| Chemical Name: | 8-(4-Dibenzothienyl)-2-(4-morpholinyl)-4H-1-benzopyran-4-one |
| Purity: | ≥99% (HPLC) |
Potent and selective inhibitor of Chk1 and Wee1
| Chemical Name: | 9-Hydroxy-4-phenyl-pyrrolo[3,4-c]carbazole-1,3(2H,6H)-dione |
| Purity: | ≥98% (HPLC) |
Selective DNA-PK inhibitor
| Chemical Name: | 2-(4-Morpholinyl)-4H-naphthol[1,2-b]pyran-4-one |
| Purity: | ≥98% (HPLC) |
Selective Chk1 inhibitor
| Alternate Names: | PF-0044736 |
| Chemical Name: | (R)-α-Amino-N-[5,6-dihydro-2-(1-methyl-1H-pyrazol-4-yl)-6-oxo-1H-pyrrolo[4,3,2-ef][2,3]benzodiazepin-8-yl]-cyclohexaneacetamide |
| Purity: | ≥99% (HPLC) |
Potent and selective Wee1 inhibitor
| Alternate Names: | AZD 1775,MK 1775 |
| Chemical Name: | 1,2-Dihydro-1-[6-(1-hydroxy-1-methylethyl)-2-pyridinyl]-6-[[4-(4-methyl-1-piperazinyl)phenyl]amino]-2-(2-propen-1-yl)-3H-pyrazolo[3,4-d]pyrimidin-3-one |
| Purity: | ≥98% (HPLC) |
Selective Chk2 inhibitor
| Alternate Names: | DDUG |
| Chemical Name: | 2,2'-[Carbonylbis(imino-4,1-phenyleneethylidyne]bishydrazinecarboximidamide) bis(4-methylbenzenesulfonate) |
| Purity: | ≥98% (HPLC) |
Chk1 inhibitor
| Chemical Name: | 9,10,11,12-Tetrahydro- 9,12-epoxy-1H-diindolo[1,2,3-fg:3',2',1'-kl]pyrrolo[3,4-i][1,6]benzodiazocine-1,3(2H)-dione |
| Purity: | ≥98% (HPLC) |
MRN-ATM pathway inhibitor
| Chemical Name: | Z-5-(4-Hydroxybenzylidene)-2-imino-1,3-thiazolidin-4-one |
| Purity: | ≥99% (HPLC) |
Dual DNA-PK and PI 3-K inhibitor
| Chemical Name: | 4-Ethyl-N-[4-[2-(4-morpholinyl)-4-oxo-4H-1-benzopyran-8-yl]-1-dibenzothienyl]-1-piperazineacetamide |
| Purity: | ≥97% (HPLC) |
Cdk inhibitor; potently inhibits cdk9; also inhibits MK2
| Chemical Name: | 1,5,6,7-Tetrahydro-2-(4-pyridinyl)-4H-pyrrolo[3,2-c]pyridin-4-one hydrochloride |
| Purity: | ≥99% (HPLC) |
