CLEC-2/CLEC1B Products
CLEC-2 (C-type lectin-like receptor 2), also known as CLEC-1B, is a transmembrane glycoprotein that is expressed on platelets, megakaryocyte, and liver sinusoidal cells. CLEC-2 binding to Podoplanin triggers platelet activation, shedding of GPVI, and cleavage of Fcgamma RIIA/CD32a. CLEC-2 expression on platelets is required for the development of lymphatic vessels and valves as well as the maintenance of lymph node high endothelial veinules (HEV) during lymphocyte crossing.
CLEC-2 additionally binds to fucoidan, HIV-1, and the platelet-aggregating snake venom protein Rhodocytin/Aggretin. In the liver, soluble CLEC-2 promotes M2 macrophage differentiation and limits inflammatory cytokine production.
Products:
55 results for "CLEC-2/CLEC1B" in Products
55 results for "CLEC-2/CLEC1B" in Products
CLEC-2/CLEC1B Products
CLEC-2 (C-type lectin-like receptor 2), also known as CLEC-1B, is a transmembrane glycoprotein that is expressed on platelets, megakaryocyte, and liver sinusoidal cells. CLEC-2 binding to Podoplanin triggers platelet activation, shedding of GPVI, and cleavage of Fcgamma RIIA/CD32a. CLEC-2 expression on platelets is required for the development of lymphatic vessels and valves as well as the maintenance of lymph node high endothelial veinules (HEV) during lymphocyte crossing.
CLEC-2 additionally binds to fucoidan, HIV-1, and the platelet-aggregating snake venom protein Rhodocytin/Aggretin. In the liver, soluble CLEC-2 promotes M2 macrophage differentiation and limits inflammatory cytokine production.
Products:
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #AYP1 |
| Applications: | ICC/IF, Flow, IP, CyTOF-ready, Func |
![CLEC-2/CLEC-1B Antibody (AYP1) [Alexa Fluor® 350]](https://resources.bio-techne.com/images/products/nbp2-50166af350_mouse-clec-2-clec-1b-mab-ayp1-alexa-fluor-350-288202315231735.jpg "CLEC-2/CLEC-1B Antibody (AYP1) [Alexa Fluor® 350] [NBP2-50166AF350] -")
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #004 |
| Applications: | ELISA |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #004 |
| Applications: | ELISA |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #004 |
| Applications: | ELISA |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #AYP2 |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #AYP1 |
| Applications: | ICC/IF, Flow, IP, CyTOF-ready, Func |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #AYP1 |
| Applications: | ICC/IF, Flow, IP, CyTOF-ready, Func |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #AYP2 |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #AYP2 |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #AYP1 |
| Applications: | ICC/IF, Flow, IP, CyTOF-ready, Func |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #AYP1 |
| Applications: | ICC/IF, Flow, IP, CyTOF-ready, Func |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #AYP1 |
| Applications: | ICC/IF, Flow, IP, CyTOF-ready, Func |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #AYP1 |
| Applications: | ICC/IF, Flow, IP, CyTOF-ready, Func |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #AYP1 |
| Applications: | ICC/IF, Flow, IP, CyTOF-ready, Func |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #AYP2 |
| Applications: | WB |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #004 |
| Applications: | ELISA |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #AYP1 |
| Applications: | ICC/IF, Flow, IP, CyTOF-ready, Func |
![CLEC-2/CLEC-1B Antibody (AYP1) [mFluor Violet 610 SE]](https://resources.bio-techne.com/images/products/nbp2-50166mfv610_mouse-clec-2-clec-1b-mab-ayp1-mfluor-violet-610-se-6720239113936.png "CLEC-2/CLEC-1B Antibody (AYP1) [mFluor Violet 610 SE] [NBP2-50166MFV610] -")
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #AYP2 |
| Applications: | WB |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #004 |
| Applications: | ELISA |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #004 |
| Applications: | ELISA |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #AYP2 |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #AYP2 |
| Applications: | WB |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #004 |
| Applications: | ELISA |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #AYP2 |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #AYP2 |
| Applications: | WB |