CXCR2/IL-8RB Products
CXCR2/IL-8RB is a member of the CXC chemokine receptor subfamily. Similar to other chemokine receptors, it is a G protein-coupled receptor (GPCR). Human CXCR2/IL-8RB is 360 amino acids (aa) in length with a predicted molecular weight of 41 kDa. The human protein shares 71% aa sequence identity with the mouse and rat protein. CXCR2/IL-8RB is expressed on neutrophils and activates neutrophil chemotaxis.
Similar to the closely related CXCR1/IL-8RA, CXCR2/IL-8RB binds and mediates CXCL8/IL-8-induced neutrophil activation. It also binds additional CXC chemokine ligands that contain an ELR aa motif. CXCR2/IL-8RB is implicated in neurological and pulmonary inflammatory diseases and injury. As such, it is a therapeutic target of interest in inflammatory disease and cancer.
Products:
307 results for "CXCR2/IL-8RB" in Products
307 results for "CXCR2/IL-8RB" in Products
CXCR2/IL-8RB Products
CXCR2/IL-8RB is a member of the CXC chemokine receptor subfamily. Similar to other chemokine receptors, it is a G protein-coupled receptor (GPCR). Human CXCR2/IL-8RB is 360 amino acids (aa) in length with a predicted molecular weight of 41 kDa. The human protein shares 71% aa sequence identity with the mouse and rat protein. CXCR2/IL-8RB is expressed on neutrophils and activates neutrophil chemotaxis.
Similar to the closely related CXCR1/IL-8RA, CXCR2/IL-8RB binds and mediates CXCL8/IL-8-induced neutrophil activation. It also binds additional CXC chemokine ligands that contain an ELR aa motif. CXCR2/IL-8RB is implicated in neurological and pulmonary inflammatory diseases and injury. As such, it is a therapeutic target of interest in inflammatory disease and cancer.
Products:
| Reactivity: | Mouse |
| Details: | Rat IgG2a Monoclonal Clone #242216 |
| Applications: | Flow, IHC, CyTOF-reported, Neut |
Clone 48311 was used by HLDA to establish CD designation
| Reactivity: | Human |
| Details: | Mouse IgG2a Monoclonal Clone #48311 |
| Applications: | Flow, IHC, CyTOF-ready, Neut |
| Reactivity: | Mouse |
| Details: | Rat IgG2a Monoclonal Clone #242216 |
| Applications: | Flow |
Clone 48311 was used by HLDA to establish CD designation
| Reactivity: | Human |
| Details: | Mouse IgG2a Monoclonal Clone #48311 |
| Applications: | Flow |
| Reactivity: | Mouse |
| Details: | Rat IgG2a Monoclonal Clone #242216 |
| Applications: | Flow |
Clone 48311 was used by HLDA to establish CD designation
| Reactivity: | Human |
| Details: | Mouse IgG2a Monoclonal Clone #48311 |
| Applications: | Flow |
| Reactivity: | Rat |
| Details: | Mouse IgG2b Monoclonal Clone #866614 |
| Applications: | Flow, CyTOF-ready |
| Reactivity: | Human |
| Details: | Mouse IgG1 kappa Monoclonal Clone #5E8-C7-F10 |
| Applications: | IHC, Flow |
![Immunohistochemistry-Paraffin: CXCR2/IL-8RB Antibody (5E8-C7-F10) - BSA Free [NBP1-43338]](https://resources.bio-techne.com/images/products/CXCR2-IL-8-RB-Antibody-5E8-C7-F10-Immunohistochemistry-Paraffin-NBP1-43338-img0005.jpg "Immunohistochemistry-Paraffin: CXCR2/IL-8RB Antibody (5E8-C7-F10) - BSA Free [NBP1-43338]")
| Reactivity: | Rat |
| Details: | Mouse IgG2b Monoclonal Clone #866614 |
| Applications: | Flow |
| Reactivity: | Mouse |
| Details: | Rat IgG2a Monoclonal Clone #242216 |
| Applications: | Flow |
| Reactivity: | Mouse |
| Details: | Rat IgG2a Monoclonal Clone #242216 |
| Applications: | Flow |
| Reactivity: | Rat |
| Details: | Mouse IgG2b Monoclonal Clone #866614 |
| Applications: | Flow |
| Reactivity: | Human, Mouse |
| Details: | Mouse IgG2A Monoclonal Clone #547 |
| Applications: | WB, ICC/IF |
![Western Blot: CXCR2/IL-8RB Antibody (547) [NBP2-43810]](https://resources.bio-techne.com/images/products/CXCR2-IL-8RB-Antibody-547-Western-Blot-NBP2-43810-img0004.jpg "Western Blot: CXCR2/IL-8RB Antibody (547) [NBP2-43810]")
| Reactivity: | Rat |
| Details: | Mouse IgG2b Monoclonal Clone #866614 |
| Applications: | Flow |
| Reactivity: | Mouse |
| Details: | Rat IgG2a Monoclonal Clone #242216 |
| Applications: | Flow |
| Reactivity: | Mouse |
| Details: | Rat IgG2a Monoclonal Clone #242216 |
| Applications: | Flow |
| Reactivity: | Human |
| Details: | Mouse IgG2 Monoclonal Clone #MM0222-7J40 |
| Applications: | IHC, WB, Flow, CyTOF-ready, B/N |
![Immunohistochemistry-Paraffin: CXCR2/IL-8RB Antibody (MM0222-7J40) - Azide and BSA Free [NBP2-12413]](https://resources.bio-techne.com/images/products/CXCR2-IL-8-RB-Antibody-MM0222-7J40-Immunohistochemistry-Paraffin-NBP2-12413-img0001.jpg "Immunohistochemistry-Paraffin: CXCR2/IL-8RB Antibody (MM0222-7J40) - Azide and BSA Free [NBP2-12413]")
| Reactivity: | Mouse |
| Details: | Rat IgG2a Monoclonal Clone #242216 |
| Applications: | Flow |
Recombinant Monoclonal Antibody
| Reactivity: | Rat |
| Details: | Mouse IgG2b Monoclonal Clone #866614R |
| Applications: | Flow |
Recombinant Monoclonal Antibody
| Reactivity: | Rat |
| Details: | Mouse IgG2b Monoclonal Clone #866614R |
| Applications: | Flow |
Recombinant Monoclonal Antibody
| Reactivity: | Rat |
| Details: | Mouse IgG2b Monoclonal Clone #866614R |
| Applications: | Flow |
Clone 48311 was used by HLDA to establish CD designation
| Reactivity: | Human |
| Details: | Mouse IgG2a Monoclonal Clone #48311 |
| Applications: | Flow |
Recombinant Monoclonal Antibody.
| Reactivity: | Rat |
| Details: | Mouse IgG2b Monoclonal Clone #866614R |
| Applications: | Flow, CyTOF-ready |
