Cytohesin-1 Products
Cytohesin-1, previously called B2-1 or PSCD1 (pleckstrin homology, Sec7 and coiled-coil domain-containing protein 1), is a member of the cytohesin family of guanine nucleotide exchange factors. The Sec7 domain binds the integrin beta 2 subunit cytoplasmic domain, activating integrins via inside-out signaling. It also independently mediates nucleotide exchange. Cytohesin-1 is primarily found in immune system cells.
8 results for "Cytohesin-1" in Products
8 results for "Cytohesin-1" in Products
Cytohesin-1 Products
Cytohesin-1, previously called B2-1 or PSCD1 (pleckstrin homology, Sec7 and coiled-coil domain-containing protein 1), is a member of the cytohesin family of guanine nucleotide exchange factors. The Sec7 domain binds the integrin beta 2 subunit cytoplasmic domain, activating integrins via inside-out signaling. It also independently mediates nucleotide exchange. Cytohesin-1 is primarily found in immune system cells.
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
Sec7-specific GEF inhibitor; selective for cytohesin family
| Chemical Name: | N-[4-[5-(1,3-Benzodioxol-5-yl)-3-methoxy-1H-1,2,4-triazol-1-yl]phenyl]-2-(phenylthio)acetamide |
| Purity: | ≥98% (HPLC) |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #6G11 |
| Applications: | IHC, WB, ICC/IF, IP |
![Immunocytochemistry/ Immunofluorescence: Cytohesin-1 Antibody (6G11) [NBP2-22513]](https://resources.bio-techne.com/images/products/Cytohesin-1-Antibody-6G11-Immunocytochemistry-Immunofluorescence-NBP2-22513-img0006.jpg "Immunocytochemistry/ Immunofluorescence: Cytohesin-1 Antibody (6G11) [NBP2-22513]")
| Reactivity: | Human |
| Details: | Mouse IgG1 kappa Monoclonal Clone #1D6 |
| Applications: | IHC, WB, ELISA, ICC/IF |
![Immunocytochemistry/ Immunofluorescence: Cytohesin-1 Antibody (1D6) [H00009267-M01]](https://resources.bio-techne.com/images/products/Cytohesin-1-Antibody-1D6-Immunocytochemistry-Immunofluorescence-H00009267-M01-img0005.jpg "Immunocytochemistry/ Immunofluorescence: Cytohesin-1 Antibody (1D6) [H00009267-M01]")
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #2E11 |
| Applications: | WB, ICC/IF, Flow |
![Immunocytochemistry/ Immunofluorescence: Cytohesin-1 Antibody (2E11) [NBP2-22512]](https://resources.bio-techne.com/images/products/Cytohesin-1-Antibody-2E+11-Immunocytochemistry-Immunofluorescence-NBP2-22512-img0003.jpg "Immunocytochemistry/ Immunofluorescence: Cytohesin-1 Antibody (2E11) [NBP2-22512]")
| Applications: | WB |
![Western Blot: Cytohesin-1 Overexpression Lysate [NBP2-10540]](https://resources.bio-techne.com/images/products/Cytohesin-1-Overexpression-Lysate-Adult-Normal-Western-Blot-NBP2-10540-img0001.jpg "Western Blot: Cytohesin-1 Overexpression Lysate [NBP2-10540]")
| Reactivity: | Human, Zebrafish |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB |
![Western Blot: Cytohesin-1 Antibody [NBP2-15082]](https://resources.bio-techne.com/images/products/Cytohesin-1-Antibody-Western-Blot-NBP2-15082-img0001.jpg "Western Blot: Cytohesin-1 Antibody [NBP2-15082]")
| Applications: | PAGE |
![SDS-PAGE: Recombinant Human Cytohesin-1 His Protein [NBP2-52108]](https://resources.bio-techne.com/images/products/Cytohesin-1-Recombinant-Protein-SDS-Page-NBP2-52108-img0001.jpg "SDS-PAGE: Recombinant Human Cytohesin-1 His Protein [NBP2-52108]")