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Desmocollin-2 Products

DSC2 belongs to the cadherin family of adhesion molecules. It is a principal component of epithelial cell desmosomes and interacts homophilically as well as heterophilically with Desmoglein-2. DSC2 is the only desmocollin that is normally expressed in simple epithelia of the GI tract, although it is downregulated during colon carcinogenesis. A variety of DSC2 mutations are associated with the cardiac arrythmia disorder ARVC.

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3 results for "Desmocollin-2" in Products

3 results for "Desmocollin-2" in Products

Desmocollin-2 Products

DSC2 belongs to the cadherin family of adhesion molecules. It is a principal component of epithelial cell desmosomes and interacts homophilically as well as heterophilically with Desmoglein-2. DSC2 is the only desmocollin that is normally expressed in simple epithelia of the GI tract, although it is downregulated during colon carcinogenesis. A variety of DSC2 mutations are associated with the cardiac arrythmia disorder ARVC.

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Applications: IHC
Reactivity: Mouse
Applications: WB, IP
Reactivity: Human
Applications: WB
Reactivity: Human
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