DNA-PKcs Products
DNA-PKcs (DNA-dependent protein kinase catalytic subunit) is a member of the PI 3-kinase related kinase (PIKK) superfamily. DNA-PKcs is a serine/threonine kinase that, along with the DNA-binding proteins Ku70/Ku80, binds to regions of DNA double strand breaks, and is involved in double-strand break repair and VDJ recombination.
52 results for "DNA-PKcs" in Products
52 results for "DNA-PKcs" in Products
DNA-PKcs Products
DNA-PKcs (DNA-dependent protein kinase catalytic subunit) is a member of the PI 3-kinase related kinase (PIKK) superfamily. DNA-PKcs is a serine/threonine kinase that, along with the DNA-binding proteins Ku70/Ku80, binds to regions of DNA double strand breaks, and is involved in double-strand break repair and VDJ recombination.
Potent and selective DNA-PK inhibitor
| Alternate Names: | KU 57788 |
| Chemical Name: | 8-(4-Dibenzothienyl)-2-(4-morpholinyl)-4H-1-benzopyran-4-one |
| Purity: | ≥99% (HPLC) |
Inhibitor of PI 3-kinase, mTOR and DNA-PK
| Chemical Name: | 3-[4-(4-Morpholinylpyrido[3',2':4,5]furo[3,2-d]pyrimidin-2-yl]phenol hydrochloride |
| Purity: | ≥98% (HPLC) |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, IP, KD |
![Western Blot: DNA-PKcs Antibody [NB100-658]](https://resources.bio-techne.com/images/products/DNA-PKcs-Antibody-Western-Blot-NB100-658-img0025.jpg "Western Blot: DNA-PKcs Antibody [NB100-658]")
| Reactivity: | Human, Mouse |
| Details: | Mouse IgG1 Monoclonal Clone #3H6 |
| Applications: | IHC, WB, ELISA, ICC/IF |
![Western Blot: DNA-PKcs Antibody (3H6)BSA Free [NBP2-22128]](https://resources.bio-techne.com/images/products/DNA-PKcs-Antibody-3H6-Western-Blot-NBP2-22128-img0006.jpg "Western Blot: DNA-PKcs Antibody (3H6)BSA Free [NBP2-22128]")
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, ICC/IF |
![Immunocytochemistry/ Immunofluorescence: DNA-PKcs Antibody [NBP2-33995]](https://resources.bio-techne.com/images/products/DNA-PKcs-Antibody-Immunocytochemistry-Immunofluorescence-NBP2-33995-img0006.jpg "Immunocytochemistry/ Immunofluorescence: DNA-PKcs Antibody [NBP2-33995]")
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ELISA, IP |
![Western Blot: DNA-PKcs [p Thr2609] Antibody [NB600-897]](https://resources.bio-techne.com/images/products/DNA-PKcs-[p-Thr2609]-Antibody-Western-Blot-NB600-897-img0005.jpg "Western Blot: DNA-PKcs [p Thr2609] Antibody [NB600-897]")
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, IP |
![Western Blot: DNA-PKcs Antibody [NB100-657]](https://resources.bio-techne.com/images/products/DNA-PKcs-Antibody-Western-Blot-NB100-657-img0003.jpg "Western Blot: DNA-PKcs Antibody [NB100-657]")
Potent and selective DNA-PK inhibitor; enhances CRISPR-mediated HDR efficiency
| Chemical Name: | 7,9-Dihydro-7-methyl-2-[(7-methyl[1,2,4]triazolo[1,5-a]pyridin-6-yl)amino]-9-(tetrahydro-2H-pyran-4-yl)-8H-purin-8-one |
| Purity: | ≥98% (HPLC) |
Highly potent PI 3-kinase inhibitor; also potent inhibitor of mTOR and DNA-PK
| Alternate Names: | GSK2126458 |
| Chemical Name: | 2,4-Difluoro-N-[2-methoxy-5-[4-(4-pyridazinyl)-6-quinolinyl]-3-pyridinyl]benzenesulfonamide |
| Purity: | ≥98% (HPLC) |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #SR1789 |
| Applications: | IHC, WB, ICC/IF |
Selective DNA-PK inhibitor
| Chemical Name: | 2-(4-Morpholinyl)-4H-naphthol[1,2-b]pyran-4-one |
| Purity: | ≥98% (HPLC) |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, IP |
![Western Blot: DNA-PKcs Antibody [NB100-659]](https://resources.bio-techne.com/images/products/DNA-PKcs-Antibody-Western-Blot-NB100-659-img0001.jpg "Western Blot: DNA-PKcs Antibody [NB100-659]")
Dual DNA-PK and PI 3-K inhibitor
| Chemical Name: | 4-Ethyl-N-[4-[2-(4-morpholinyl)-4-oxo-4H-1-benzopyran-8-yl]-1-dibenzothienyl]-1-piperazineacetamide |
| Purity: | ≥97% (HPLC) |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ICC/IF |
![Western Blot: DNA-PKcs [p Ser2056] Antibody [NBP3-13142]](https://resources.bio-techne.com/images/products/DNA-PKcs-[p-Ser2056]-Antibody-Western-Blot-NBP3-13142-img0003.jpg "Western Blot: DNA-PKcs [p Ser2056] Antibody [NBP3-13142]")
| Applications: | WB, ELISA, MA, AP |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ICC/IF |
![Western Blot: DNA-PKcs [p Ser2056] AntibodyAzide and BSA Free [NBP3-05444]](https://resources.bio-techne.com/images/products/DNA-PKcs-[p-Ser2056]-Antibody-Western-Blot-NBP3-05444-img0002.jpg "Western Blot: DNA-PKcs [p Ser2056] AntibodyAzide and BSA Free [NBP3-05444]")
Dual kinase inhibitor; inhibits PI 3-K family kinases
| Chemical Name: | 1-Cyclopentyl-3-(1H-pyrrolo[2,3-b]pyridin-5-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine |
| Purity: | ≥98% (HPLC) |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #2-B3-R |
| Applications: | IHC, WB, ICC/IF |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, IP |
![Western Blot: DNA-PKcs Antibody [NB100-660]](https://resources.bio-techne.com/images/products/DNA-PKcs-Antibody-Western-Blot-NB100-660-img0002.jpg "Western Blot: DNA-PKcs Antibody [NB100-660]")
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #JE41-92 |
| Applications: | WB, ICC/IF |
![DNA-PKcs [p Ser2056] Antibody (JE41-92)](https://resources.bio-techne.com/images/products/nbp3-32759_rabbit-dna-pkcs-p-ser2056-mab-je41-92-288202412442994.jpg "Western Blot: DNA-PKcs [p Ser2056] Antibody (JE41-92) [NBP3-32759]")
Recombinant monoclonal antibody expressed in HEK293F cells
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #4A4 |
| Applications: | ELISA, ICC/IF |
![DNA-PKcs [p Ser2056] Antibody (4A4)](https://resources.bio-techne.com/images/products/nbp3-26398_rabbit-dna-pkcs-p-ser-2056-mab-4a4-28220241323634.jpg "Immunocytochemistry/Immunofluorescence: DNA-PKcs [p Ser2056] Antibody (4A4) [NBP3-26398] -")
| Applications: | AC |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #3H6 |
| Applications: | IHC, WB, ELISA, ICC/IF |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #3H6 |
| Applications: | IHC, WB, ELISA, ICC/IF |