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DUSP12 Products

DUSP12 is encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product is the human ortholog of the Saccharomyces cerevisiae YVH1 protein tyrosine phosphatase. It is localized predominantly in the nucleus, and is novel in that it contains, and is regulated by a zinc finger domain.
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35 results for "DUSP12" in Products

35 results for "DUSP12" in Products

DUSP12 Products

DUSP12 is encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product is the human ortholog of the Saccharomyces cerevisiae YVH1 protein tyrosine phosphatase. It is localized predominantly in the nucleus, and is novel in that it contains, and is regulated by a zinc finger domain.
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Applications: WB, ICC/IF
Reactivity: Human
Applications: WB, IP
Reactivity: Human
Applications: WB
Reactivity: Human
Applications: WB, ELISA, MA, AP
Catalog #: H00011266-Q01
Applications: WB, ELISA, MA, AP, PAGE
Applications: WB
Reactivity: Human
Applications: WB
Reactivity: Human
Applications: WB
Applications: IHC
Reactivity: Human
Applications: AC
Applications: WB, IP
Reactivity: Human
Applications: WB, IP
Reactivity: Human
Applications: WB, IP
Reactivity: Human
Applications: WB, IP
Reactivity: Human
Applications: WB, IP
Reactivity: Human
Applications: WB, IP
Reactivity: Human
Applications: WB, IP
Reactivity: Human
Applications: WB, IP
Reactivity: Human
Applications: WB, IP
Reactivity: Human
Applications: WB, IP
Reactivity: Human
Applications: WB, IP
Reactivity: Human
Applications: WB, IP
Reactivity: Human
Applications: WB, IP
Reactivity: Human
Applications: WB, IP
Reactivity: Human
Applications: WB, IP
Reactivity: Human
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