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E-Cadherin Products

E-Cadherin/Cadherin-1 (ECAD) Is a transmembrane cell adhesion protein. It forms homophilic clusters between epithelial cells and is a critical component of adherens junctions. These junctions are critical for the maintenance of the epithelial barrier and epithelial tissue homeostasis. Decreased E-Cadherin is associated with physiological and pathological epithelial-to-mesenchymal transition (EMT) and cell migration, and E-Cadherin loss contributes to cancer metastasis. The shed ECD is released as a soluble factor that enhances cancer cell motility and EGFR-dependent survival and proliferation.

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14 results for "E-Cadherin" in Products

14 results for "E-Cadherin" in Products

E-Cadherin Products

E-Cadherin/Cadherin-1 (ECAD) Is a transmembrane cell adhesion protein. It forms homophilic clusters between epithelial cells and is a critical component of adherens junctions. These junctions are critical for the maintenance of the epithelial barrier and epithelial tissue homeostasis. Decreased E-Cadherin is associated with physiological and pathological epithelial-to-mesenchymal transition (EMT) and cell migration, and E-Cadherin loss contributes to cancer metastasis. The shed ECD is released as a soluble factor that enhances cancer cell motility and EGFR-dependent survival and proliferation.

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Applications: IHC, WB, ICC/IF, Flow, IP
Reactivity: Human, Mouse, Rat

Recombinant Monoclonal Antibody.

Applications: IHC, WB, ICC/IF, IP, Func
Reactivity: Human, Mouse, Rat, Canine, Zebrafish
Applications: WB, IP
Reactivity: Human, Mouse, Rat
Applications: WB, ELISA, ICC/IF
Reactivity: Rat
Applications: WB, ELISA, ICC/IF
Reactivity: Rat
Applications: WB, ICC/IF, ELISA
Reactivity: Rat
Applications: WB, ELISA, ICC/IF
Reactivity: Rat
Applications: WB, ELISA, ICC/IF
Reactivity: Rat
Applications: WB, ELISA, ICC/IF
Reactivity: Rat
Applications: WB, ELISA, ICC/IF
Reactivity: Rat
Applications: WB, ELISA, ICC/IF
Reactivity: Rat
Applications: WB, ELISA, ICC/IF
Reactivity: Rat
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