E-Cadherin Products
E-Cadherin/Cadherin-1 (ECAD) Is a transmembrane cell adhesion protein. It forms homophilic clusters between epithelial cells and is a critical component of adherens junctions. These junctions are critical for the maintenance of the epithelial barrier and epithelial tissue homeostasis. Decreased E-Cadherin is associated with physiological and pathological epithelial-to-mesenchymal transition (EMT) and cell migration, and E-Cadherin loss contributes to cancer metastasis. The shed ECD is released as a soluble factor that enhances cancer cell motility and EGFR-dependent survival and proliferation.
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1 result for "E-Cadherin" in Products
E-Cadherin Products
E-Cadherin/Cadherin-1 (ECAD) Is a transmembrane cell adhesion protein. It forms homophilic clusters between epithelial cells and is a critical component of adherens junctions. These junctions are critical for the maintenance of the epithelial barrier and epithelial tissue homeostasis. Decreased E-Cadherin is associated with physiological and pathological epithelial-to-mesenchymal transition (EMT) and cell migration, and E-Cadherin loss contributes to cancer metastasis. The shed ECD is released as a soluble factor that enhances cancer cell motility and EGFR-dependent survival and proliferation.
| Reactivity: | Human, Mouse, Rat, Canine, Zebrafish |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF, IP, Func |
![Immunocytochemistry/ Immunofluorescence: E-Cadherin Antibody [NBP2-16258]](https://resources.bio-techne.com/images/products/E-Cadherin-Antibody-Immunocytochemistry-Immunofluorescence-NBP2-16258-img0018.jpg "Immunocytochemistry/ Immunofluorescence: E-Cadherin Antibody [NBP2-16258]")