E-Selectin/CD62E Products
E-Selectin, also known as CD62E, is expressed on vascular endothelial cells in response to IL-1 beta and TNF-alpha. It is a lectin that binds to sialylated or fucosylated molecules on neutrophils, monocytes, and a subset of memory T cells. E-Selectin mediates the initial attachment of circulating leukocytes to the blood vessel wall during inflammation. This interaction permits leukocytes to roll along the vascular endothelium. Subsequent ICAM-1 and VCAM-1 mediated adhesion leads to extravasation of the leukocyte through the blood vessel wall into the extracellular matrix tissue.
Products:
9 results for "E-Selectin/CD62E" in Products
9 results for "E-Selectin/CD62E" in Products
E-Selectin/CD62E Products
E-Selectin, also known as CD62E, is expressed on vascular endothelial cells in response to IL-1 beta and TNF-alpha. It is a lectin that binds to sialylated or fucosylated molecules on neutrophils, monocytes, and a subset of memory T cells. E-Selectin mediates the initial attachment of circulating leukocytes to the blood vessel wall during inflammation. This interaction permits leukocytes to roll along the vascular endothelium. Subsequent ICAM-1 and VCAM-1 mediated adhesion leads to extravasation of the leukocyte through the blood vessel wall into the extracellular matrix tissue.
Products:
Clone BBIG-E4 was used by HLDA to establish CD designation
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #BBIG-E4 |
| Applications: | WB, Flow, IHC, IP, ICC |
| Sensitivity: | 0.027 ng/mL |
| Applications: | ELISA |
| Assay Range: | 0.125 - 8 ng/mL (Cell Culture Supernates, Serum, Heparin Plasma, Citrate Plasma) |
| Source: | NS0 |
| Accession #: | P16581 |
| Applications: | BA |
| Source: | NS0 |
| Accession #: | Q00690 |
| Applications: | BA |
| Reactivity: | Human |
| Details: | Goat Serum Polyclonal |
| Applications: | WB, IHC |
| Assay Range: | 93.8 - 6,000 pg/mL |
| Applications: | ELISA |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #BBIG-E5 |
| Applications: | Flow |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #BBIG-E5 |
| Applications: | WB, ICC |
| Reactivity: | Human |
| Details: | Sheep IgG Polyclonal |
| Applications: | WB, AdBlk |