EGFR Products
EGFR (epidermal growth factor receptor), also known as HER-1, ErbB1, or ErbB, is a transmembrane receptor tyrosine kinase that binds a subset of the EGF family ligands including EGF, Amphiregulin, TGF-alpha, Betacellulin, Epiregulin, HB-EGF, and Epigen. Ligand binding induces EGFR homodimerization as well as heterdimerization with ErbB2, resulting in kinase activation, tyrosine phosphorylation, and cell signaling. EGFR can also be recruited to form heterodimers with the ligand-activated ErbB3 or ErbB4.
EGFR signaling regulates multiple biological functions including cell proliferation, differentiation, motility, and apoptosis. EGFR is overexpressed in a wide variety of tumors and is the target of several anti-cancer drugs. Soluble receptors consisting of the extracellular ligand binding domain are generated by alternate splicing in human and mouse.
Products:
1063 results for "EGFR" in Products
1063 results for "EGFR" in Products
EGFR Products
EGFR (epidermal growth factor receptor), also known as HER-1, ErbB1, or ErbB, is a transmembrane receptor tyrosine kinase that binds a subset of the EGF family ligands including EGF, Amphiregulin, TGF-alpha, Betacellulin, Epiregulin, HB-EGF, and Epigen. Ligand binding induces EGFR homodimerization as well as heterdimerization with ErbB2, resulting in kinase activation, tyrosine phosphorylation, and cell signaling. EGFR can also be recruited to form heterodimers with the ligand-activated ErbB3 or ErbB4.
EGFR signaling regulates multiple biological functions including cell proliferation, differentiation, motility, and apoptosis. EGFR is overexpressed in a wide variety of tumors and is the target of several anti-cancer drugs. Soluble receptors consisting of the extracellular ligand binding domain are generated by alternate splicing in human and mouse.
Products:
Analyzed by SEC-MALS
| Source: | NS0 |
| Accession #: | CAA25240.1 |
| Applications: | Bind |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Rabbit IgG Kappa Monoclonal Clone #EGFR/8933R |
| Applications: | IHC |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, Simple Western, Flow, IHC, IP, +3 More |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Human IgG1 Monoclonal Clone #Chinese Mil.Med.Sci. patent anti-EGFR |
| Applications: | ELISA, Flow, Func |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Human IgG1 Monoclonal Clone #Regeneron patent anti-EGFR |
| Applications: | ELISA, Flow, Func |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Rabbit IgG Kappa Monoclonal Clone #EGFR/9166R |
| Applications: | IHC |
![EGFR Antibody (EGFR/9166R) Immunohistochemistry-Paraffin: EGFR Antibody (EGFR/9166R) [NBP3-23767] -](https://resources.bio-techne.com/images/products/nbp3-23767_rabbit-egfr-mab-egfr-9166r-2412025872339.jpg "Immunohistochemistry-Paraffin: EGFR Antibody (EGFR/9166R) [NBP3-23767] -")
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Rabbit IgG Kappa Monoclonal Clone #EGFR/8933R |
| Applications: | IHC |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Human IgG1 Monoclonal Clone #Regeneron patent anti-EGFR |
| Applications: | ELISA, Flow, Func |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Rabbit IgG Kappa Monoclonal Clone #EGFR/8933R |
| Applications: | IHC |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Rabbit IgG Kappa Monoclonal Clone #EGFR/8933R |
| Applications: | IHC |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Rabbit IgG Kappa Monoclonal Clone #EGFR/9166R |
| Applications: | IHC |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Human IgG1 Monoclonal Clone #Chinese Mil.Med.Sci. patent anti-EGFR |
| Applications: | ELISA, Flow, Func |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Human IgG1 Monoclonal Clone #Regeneron patent anti-EGFR |
| Applications: | ELISA, Flow, Func |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Human IgG1 Monoclonal Clone #Chinese Mil.Med.Sci. patent anti-EGFR |
| Applications: | ELISA, Flow, Func |
| Sensitivity: | 0.036 ng/mL |
| Applications: | ELISA |
| Assay Range: | 0.313 - 20 ng/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma, Human Milk) |
| Applications: | ELISA |
| Sensitivity: | 0.127 ng/mL |
| Applications: | ELISA |
| Assay Range: | 0.469 - 30 ng/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma, Urine) |
| Reactivity: | Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, Simple Western, IHC |
Recombinant Monoclonal Antibody For Research Use Only
| Reactivity: | Human |
| Details: | Human IgG1 Monoclonal Clone #Hu1 |
| Applications: | Flow |
| Source: | Sf 21 (baculovirus) |
| Accession #: | P00533.2 |
| Applications: | EnzAct |
| Reactivity: | Human |
| Details: | Mouse IgG2a Monoclonal Clone #338324 |
| Applications: | WB, CyTOF-ready, ICFlow |
| Source: | NS0 |
| Accession #: | CAA25240 |
| Applications: | BA |
Recombinant Monoclonal Antibody For Research Use Only
| Reactivity: | Human |
| Details: | Human IgG1 Monoclonal Clone #Hu1 |
| Applications: | Flow, CyTOF-ready |
Recombinant Monoclonal Antibody For Research Use Only
| Reactivity: | Human |
| Details: | Human IgG1 Monoclonal Clone #Hu1 |
| Applications: | Flow |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, Simple Western, IHC, CyTOF-ready, ICC, +1 More |
