FGF-21 Products
FGF-21 (Fibroblast Growth Factor 21) is a member of an FGF subfamily that also includes FGF-19 and FGF-23. FGF-19 subfamily members lack a heparin binding domain, enabling them to freely circulate as endocrine factors and diffuse within tissues. FGF-21 signals through Klotho beta in complex with FGF receptors. It regulates cellular metabolism including glucose uptake in adipocytes and cellular sensitivity to insulin. It is basally expressed in the pancreas, thymus, liver, and adipose tissue and is upregulated in liver, muscle, and fat in obesity and diabetes. FGF-21 also plays a role in cell survival and proliferation, mesenchymal stem cell differentiation, circadian rhythm, and controlling reproductive capacity.
29 results for "FGF-21" in Products
29 results for "FGF-21" in Products
FGF-21 Products
FGF-21 (Fibroblast Growth Factor 21) is a member of an FGF subfamily that also includes FGF-19 and FGF-23. FGF-19 subfamily members lack a heparin binding domain, enabling them to freely circulate as endocrine factors and diffuse within tissues. FGF-21 signals through Klotho beta in complex with FGF receptors. It regulates cellular metabolism including glucose uptake in adipocytes and cellular sensitivity to insulin. It is basally expressed in the pancreas, thymus, liver, and adipose tissue and is upregulated in liver, muscle, and fat in obesity and diabetes. FGF-21 also plays a role in cell survival and proliferation, mesenchymal stem cell differentiation, circadian rhythm, and controlling reproductive capacity.
Sensitivity: | 13.4 pg/mL |
Applications: | ELISA |
Assay Range: | 31.3 - 2,000 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma) |
Source: | E. coli |
Accession #: | Q9NSA1 |
Applications: | BA |
Contains 4 membranes-each spotted in duplicate with 111 different cytokine antibodies
Contains 4 membranes - each spotted in duplicate with 53 different angiogenesis antibodies
Contains 4 membranes-each spotted in duplicate with 79 different cytokine antibodies
Control for use with Human FGF-21 Simple Plex Cartridge Kit
Applications: | Ctrl, Simple Plex |
Assay Range: | 15.6 - 1,000 pg/mL |
Applications: | ELISA |
Recombinant Monoclonal Antibody.
Reactivity: | Human |
Details: | Goat IgG2b Monoclonal Clone #40020A |
Applications: | Neut |
Contains 4 membranes - each spotted in duplicate with 38 different obesity-related antibodies
Assay Range: | 31.2 - 2,000 pg/mL |
Applications: | ELISA |
Reactivity: | Human, Mouse |
Details: | Mouse IgG1 Monoclonal Clone #315901 |
Applications: | WB |
Reactivity: | Human |
Details: | Mouse IgG2b Monoclonal Clone #461804 |
Applications: | CyTOF-ready, ICC, ICFlow |
Reactivity: | Human |
Details: | Mouse IgG2b Monoclonal Clone #315914 |
Applications: | WB |
Reactivity: | Human |
Details: | Mouse IgG1 Monoclonal Clone #461801 |
Applications: | ELISA |
Control for use with Mouse/Rat FGF-21 Simple Plex Assay Cartridge Kit
Reactivity: | Human |
Details: | Mouse IgG2b Monoclonal Clone #461804 |
Applications: | ICFlow |
Reactivity: | Human |
Details: | Mouse IgG2b Monoclonal Clone #461804 |
Applications: | ICFlow |
Reactivity: | Human |
Details: | Mouse IgG2b Monoclonal Clone #461804 |
Applications: | ICFlow |
Reactivity: | Human |
Details: | Mouse IgG2b Monoclonal Clone #461804 |
Applications: | ICFlow |
Reactivity: | Human |
Details: | Mouse IgG2b Monoclonal Clone #461804 |
Applications: | ICFlow |
Reactivity: | Human |
Details: | Mouse IgG2b Monoclonal Clone #461804 |
Applications: | ICFlow |
Reactivity: | Human |
Details: | Mouse IgG2b Monoclonal Clone #461804 |
Applications: | ICFlow |
Reactivity: | Human |
Details: | Rabbit IgG Polyclonal |
Applications: | IHC, WB, ICC/IF |
Reactivity: | Rat |
Details: | Mouse IgG1 kappa Monoclonal Clone #C1 |
Applications: | IHC, WB, ICC/IF, IP, NULL |
Contains 4 membranes - each spotted in duplicate with 30 different obesity-related antibodies