Flt-3/Flk-2 Products
The Flt-3 (fms-like tyrosine kinase) receptor, also named Flk-2 (fetal liver kinase) and STK-1(stem cell tyrosine kinase) is a member of the class III subfamily of receptor tyrosine kinases that also includes c-kit, the receptor for SCF, and fms, the receptor for M-CSF. Mouse Flt-3 shares 85% amino acid sequence identity with human Flt-3. Flt-3 expression has been detected in various tissues, including placenta, gonads, and tissues of nervous and hematopoietic origin.
238 results for "Flt-3/Flk-2" in Products
238 results for "Flt-3/Flk-2" in Products
Flt-3/Flk-2 Products
The Flt-3 (fms-like tyrosine kinase) receptor, also named Flk-2 (fetal liver kinase) and STK-1(stem cell tyrosine kinase) is a member of the class III subfamily of receptor tyrosine kinases that also includes c-kit, the receptor for SCF, and fms, the receptor for M-CSF. Mouse Flt-3 shares 85% amino acid sequence identity with human Flt-3. Flt-3 expression has been detected in various tissues, including placenta, gonads, and tissues of nervous and hematopoietic origin.
Contains 4 membranes - each spotted in duplicate with 49 different RTK antibodies
Potent VEGFR, PDGFRβ and KIT inhibitor
| Alternate Names: | SU 11248 |
| Chemical Name: | N-[2-(Diethylamino)ethyl]-5-[(Z)-(5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidine)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide (2S)-2-hydroxybutanedioate salt |
| Purity: | ≥99% (HPLC) |
VEGFR inhibitor. Also inhibits KIT, RET, MET and FLT3
| Alternate Names: | Semaxinib |
| Chemical Name: | 3-[(3,5-Dimethyl-1H-pyrrol-2-yl)methylene]-1,3-dihydro-2H-indol-2-one |
| Purity: | ≥99% (HPLC) |
Contains 4 membranes - each spotted in duplicate with 39 different RTK antibodies
| Reactivity: | Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, Flow, CyTOF-ready |
| Applications: | ELISA |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #66903 |
| Applications: | Flow, CyTOF-ready |
Potent inhibitor of PDGFRβ, KDR, FLT3 and CSF-1R
| Chemical Name: | N-[4-(3-Amino-1H-indazol-4-yl)phenyl]-N'-(2-fluoro-5-methylphenyl)urea |
| Purity: | ≥98% (HPLC) |
| Reactivity: | Mouse |
| Details: | Rat IgG2a Monoclonal Clone #113308 |
| Applications: | Flow, CyTOF-ready, ICC |
| Reactivity: | Mouse |
| Details: | Rat IgG2 Monoclonal Clone #12B6 |
| Applications: | IHC, WB |
![Immunohistochemistry-Paraffin: Flt-3/Flk-2/CD135 Antibody (12B6) - Azide and BSA Free [NB110-94155]](https://resources.bio-techne.com/images/products/Flt-3-Flk-2-CD135-Antibody-12B6-Immunohistochemistry-Paraffin-NB110-94155-img0003.jpg "Immunohistochemistry-Paraffin: Flt-3/Flk-2/CD135 Antibody (12B6) - Azide and BSA Free [NB110-94155]")
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, ELISA, Flow, CyTOF-ready |
| Source: | NS0 |
| Accession #: | AAA18947 |
| Applications: | BA |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, Simple Western, ICC |
| Source: | HEK293 |
| Accession #: | P36888 |
| Applications: | BA |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #66903 |
| Applications: | Flow |
| Source: | NS0 |
| Accession #: | Q00342 |
| Applications: | BA |
Potent FLT3 inhibitor; also potently inhibits AXL
| Chemical Name: | 6-Ethyl-3-[[3-methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]amino]-5-[(tetrahydro-2H-pyran-4-yl)amino]-2-pyrazinecarboxamide |
| Purity: | ≥98% (HPLC) |
Biotinylated
| Source: | CHO |
| Accession #: | P36888.2 |
| Applications: | BA |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #66907 |
| Applications: | WB, ELISA |
| Assay Range: | 125 - 8,000 pg/mL |
| Applications: | ELISA |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #66903 |
| Applications: | Flow |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #66903 |
| Applications: | Flow |
| Reactivity: | Mouse |
| Details: | Rat IgG2a Monoclonal Clone #113308 |
| Applications: | Flow |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #66903 |
| Applications: | Flow |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #66903 |
| Applications: | Flow |
