Fyn Products
Fyn is a ubiquitously expressed member of the Src family of intracellular tyrosine kinases. Fyn functions in T cell receptor signaling, adhesion-mediated signaling, and regulation of brain function. Mice lacking fyn display various deficits, including impaired spatial memory, hypomyelination, and uncoordinated hippocampal structure, suggesting that Fyn is involved in multiple neural signaling pathways.
15 results for "Fyn" in Products
15 results for "Fyn" in Products
Fyn Products
Fyn is a ubiquitously expressed member of the Src family of intracellular tyrosine kinases. Fyn functions in T cell receptor signaling, adhesion-mediated signaling, and regulation of brain function. Mice lacking fyn display various deficits, including impaired spatial memory, hypomyelination, and uncoordinated hippocampal structure, suggesting that Fyn is involved in multiple neural signaling pathways.
Reactivity: | Human, Mouse, Zebrafish |
Details: | Rabbit IgG Polyclonal |
Applications: | WB, ICC/IF |
Reactivity: | Human |
Details: | Goat IgG Polyclonal |
Applications: | ICC |
Reactivity: | Human |
Details: | Goat IgG Polyclonal |
Applications: | WB, ELISA |
Recombinant monoclonal antibody expressed in HEK293F cells
Reactivity: | Human |
Details: | Rabbit IgG Monoclonal Clone #1G3 |
Applications: | IHC, ELISA |
Recombinant Monoclonal Antibody
Reactivity: | Human, Mouse, Rat |
Details: | Rabbit IgG Monoclonal Clone #JE42-22 |
Applications: | WB |
Contains 4 sets of 2 membranes - each spotted in duplicate with antibodies against 37 different kinases and 2 related total proteins
Potent PDGFRα and PDGFRβ inhibitor; also inhibits c-Abl, Lck, c-Src and Fyn kinases
Chemical Name: | N-(3-Fluorophenyl)-1,4-dihydro-6,7-dimethoxyindeno[1,2-c]pyrazol-3-amine |
Purity: | ≥98% (HPLC) |
Highly potent pan-Src/Bcr-Abl inhibitor
Alternate Names: | BMS-354825 |
Chemical Name: | N-(2-Chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)-1-piperazinyl]-2-methyl-4-pyrimidinyl]amino]-5-thiazolecarboxamide |
Purity: | ≥98% (HPLC) |
Potent, selective Src family kinase inhibitor
Chemical Name: | 3-(4-chlorophenyl) 1-(1,1-dimethylethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine |
Purity: | ≥99% (HPLC) |
Dual Src-Abl inhibitor; antiproliferative
Alternate Names: | SKI-606 |
Chemical Name: | 4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]-3-quinolinecarbonitrile |
Purity: | ≥99% |
Protein kinase inhibitor
Alternate Names: | SF 2370 |
Chemical Name: | (9S,10R,12R)-2,3,9,10,11,12-Hexahydro-10-hydroxy-9-methyl-1-oxo-9,12-epoxy-1H-diindolo[1,2,3-fg:3',2',1'-kl]pyrrolo[3,4-i][1,6]benzodiazocine-10-carboxylic acid methyl ester |
Purity: | ≥98% (HPLC) |
Potent and selective Src tyrosine kinase family inhibitor; anticancer; antiviral; orally bioavailable
Alternate Names: | AZD 0530 |
Chemical Name: | N-(5-Chloro-1,3-benzodioxol-4-yl)-7-[2-(4-methyl-1-piperazinyl)ethoxy]-5-[(tetrahydro-2H-pyran-4-yl)oxy]-4-quinazolinamine |
Purity: | ≥98% (HPLC) |
Src family kinase inhibitor; also inhibits c-Abl
Alternate Names: | 1-NA-PP 1 |
Chemical Name: | 1-(1,1-Dimethylethyl)-3-(1-naphthalenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine |
Purity: | ≥99% (HPLC) |
Potent ATP-competitive Src family kinase inhibitor; also AMPK inhibitor; cell permeable
Chemical Name: | 2,3-Dihydro-N,N-dimethyl-2-oxo-3-[(4,5,6,7-tetrahydro-1H-indol-2-yl)methylene]-1H-indole-5-sulfonamide |
Purity: | ≥98% (HPLC) |
Potent, selective Src family kinase inhibitor
Chemical Name: | 1-(1,1-Dimethylethyl)-1-(4-methylphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine |
Purity: | ≥98% (HPLC) |