Helios Products
Helios, also known as IKZF2, is a 70 kDa DNA-binding transcription regulator in the Ikaros family that contains four N-terminal C2H2-type zinc finger domains and two C-terminal zinc finger domains. Helios is expressed in developing hematopoietic and epithelial tissues and in adult T cells and thymic-derived regulatory T cells (Treg). It forms homodimers and also heterodimers with other Ikaros family proteins Ikaros, Pegasus, Eos, and Aiolos. Alternate splicing of human Helios generates a short isoform that lacks three of the the N-terminal zinc finger domains. This isoform is overexpressed in T cell leukemias where it can still dimerize with Ikaros proteins but functions as a dominant negative regulator.
101 results for "Helios" in Products
101 results for "Helios" in Products
Helios Products
Helios, also known as IKZF2, is a 70 kDa DNA-binding transcription regulator in the Ikaros family that contains four N-terminal C2H2-type zinc finger domains and two C-terminal zinc finger domains. Helios is expressed in developing hematopoietic and epithelial tissues and in adult T cells and thymic-derived regulatory T cells (Treg). It forms homodimers and also heterodimers with other Ikaros family proteins Ikaros, Pegasus, Eos, and Aiolos. Alternate splicing of human Helios generates a short isoform that lacks three of the the N-terminal zinc finger domains. This isoform is overexpressed in T cell leukemias where it can still dimerize with Ikaros proteins but functions as a dominant negative regulator.
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #736423 |
| Applications: | WB, IHC |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #736440 |
| Applications: | CyTOF-ready, ICFlow |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #736440 |
| Applications: | ICFlow |
| Reactivity: | Human |
| Details: | Sheep IgG Polyclonal |
| Applications: | WB, IP |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #736440 |
| Applications: | ICFlow |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #736440 |
| Applications: | ICFlow |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #736440 |
| Applications: | ICFlow |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #736440 |
| Applications: | ICFlow |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #736440 |
| Applications: | ICFlow |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #736440 |
| Applications: | ICFlow |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, IP |
![Western Blot: Helios Antibody [NBP2-04050]](https://resources.bio-techne.com/images/products/Helios-Antibody-Western-Blot-NBP2-04050-img0005.jpg "Western Blot: Helios Antibody [NBP2-04050]")
| Applications: | WB, ELISA, MA, AP |
![SDS-PAGE: Recombinant Human Helios GST (N-Term) Protein [H00022807-Q01]](https://resources.bio-techne.com/images/products/Recombinant-Human-Helios-Protein-SDS-Page-H00022807-Q01-img0002.jpg "SDS-PAGE: Recombinant Human Helios GST (N-Term) Protein [H00022807-Q01]")
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB |
![Western Blot: Helios Antibody [NBP2-16802]](https://resources.bio-techne.com/images/products/Helios-Antibody-Western-Blot-NBP2-16802-img0003.jpg "Western Blot: Helios Antibody [NBP2-16802]")
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB |
![Western Blot: Helios Antibody [NBP1-79703]](https://resources.bio-techne.com/images/products/Helios-Antibody-Western-Blot-NBP1-79703-img0003.jpg "Western Blot: Helios Antibody [NBP1-79703]")
| Reactivity: | Human, Mouse |
| Details: | Armenian Hamster IgG Monoclonal Clone #22F6 |
| Applications: | Flow, CyTOF-ready |
![Flow Cytometry: Helios Antibody (22F6) - BSA Free [NBP2-37723]](https://resources.bio-techne.com/images/products/Helios-Antibody-22F6-Flow-Cytometry-NBP2-37723-img0003.jpg "Flow Cytometry: Helios Antibody (22F6) - BSA Free [NBP2-37723]")
| Applications: | WB |
![Western Blot: Helios Overexpression Lysate [NBL1-11892]](https://resources.bio-techne.com/images/products/HELIOS-Overexpression-Lysate-Adult-Normal-Western-Blot-NBL1-11892-img0002.jpg "Western Blot: Helios Overexpression Lysate [NBL1-11892]")
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, IP |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #736440 |
| Applications: | Flow, CyTOF-ready |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, IP |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, IP |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #736440 |
| Applications: | Flow, CyTOF-ready |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #736440 |
| Applications: | Flow, CyTOF-ready |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #736440 |
| Applications: | Flow, CyTOF-ready |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #736440 |
| Applications: | Flow, CyTOF-ready |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, IP |