HMGB1/HMG-1 Products
HMGB1 (high-mobility group box 1 protein), also known as HMG1 or Amphoterin, is an intracellular protein that is regulated by multiple posttranslational modifications including acetylation, phosphorylation, and methylation. HMGB1 is released upon cell necrosis, apoptosis, and pyroptosis. It acts as a multifunctional alarmin that stimulates inflammation upon sterile or infectious insult. Receptors for HMGB1 include TLR2, TLR4, TLR9, Syndecan-3, Siglec-10, Integrin alpha M beta 2, CXCR4, TIM-3, and RAGE. It is implicated in the pathogenesis of a broad range of diseases including atherosclerosis, sepsis, cancer, neurodegenerative diseases, and autoimmunity.
Products:
240 results for "HMGB1/HMG-1" in Products
240 results for "HMGB1/HMG-1" in Products
HMGB1/HMG-1 Products
HMGB1 (high-mobility group box 1 protein), also known as HMG1 or Amphoterin, is an intracellular protein that is regulated by multiple posttranslational modifications including acetylation, phosphorylation, and methylation. HMGB1 is released upon cell necrosis, apoptosis, and pyroptosis. It acts as a multifunctional alarmin that stimulates inflammation upon sterile or infectious insult. Receptors for HMGB1 include TLR2, TLR4, TLR9, Syndecan-3, Siglec-10, Integrin alpha M beta 2, CXCR4, TIM-3, and RAGE. It is implicated in the pathogenesis of a broad range of diseases including atherosclerosis, sepsis, cancer, neurodegenerative diseases, and autoimmunity.
Products:
Source: | NS0 |
Accession #: | P09429 |
Applications: | BA |
Reactivity: | Human |
Details: | Mouse IgG2b Monoclonal Clone #115603 |
Applications: | WB, IHC, ChIP, CyTOF-ready, ICC, +1 More |
Reactivity: | Human, Mouse, Rat, Canine, Bovine, +2 More |
Details: | Rabbit IgG Polyclonal |
Applications: | IHC, WB, ELISA, ICC/IF, Flow, +3 More |
Applications: | ELISA |
Reactivity: | Human, E. coli |
Details: | Mouse IgG2a Kappa Monoclonal Clone #2F6 |
Applications: | IHC, WB, ELISA, ICC/IF, Func, +2 More |
Applications: | ELISA |
Reactivity: | Human, Mouse |
Details: | Mouse IgG2b Kappa Monoclonal Clone #19N10B7 |
Applications: | IHC, WB, Flow, IP, CyTOF-ready, +2 More |
Reactivity: | Human, Mouse, Rat |
Details: | Rat IgG2b Monoclonal Clone #951420 |
Applications: | WB, Simple Western, IHC |
Reactivity: | Human, Mouse |
Details: | Chicken IgY Polyclonal |
Applications: | WB, KO |
Reactivity: | Human, Rat |
Details: | Mouse IgG2a Kappa Monoclonal Clone #1D5 |
Applications: | IHC, WB, ELISA, ICC/IF, MA |
Reactivity: | Human |
Details: | Mouse IgG2b Monoclonal Clone #115603 |
Applications: | ICFlow |
Reactivity: | Human, Mouse, Rat |
Details: | Mouse IgG2B Monoclonal Clone #1F3 |
Applications: | IHC, WB, ICC/IF, Flow, CyTOF-ready, +2 More |
Reactivity: | Human, Mouse |
Details: | Mouse IgG1 kappa Monoclonal Clone #19N15F4 |
Applications: | IHC, WB, Flow |
Applications: | ELISA |
Reactivity: | Human, Mouse, Rat |
Details: | Rabbit IgG Polyclonal |
Applications: | IHC, WB, ELISA, ICC/IF |
Reactivity: | Human, Mouse |
Details: | Rabbit IgG Polyclonal |
Applications: | IHC, WB, Flow, Simple Western |
Recombinant Monoclonal Antibody
Reactivity: | Human, Mouse, Rat |
Details: | Rabbit IgG Monoclonal Clone #1C4T5 |
Applications: | IHC, WB, ICC/IF, KO |
Reactivity: | Human |
Details: | Mouse IgG2b Monoclonal Clone #115603 |
Applications: | ICFlow |
Reactivity: | Human, Mouse |
Details: | Mouse IgG2b Monoclonal Clone #1002147 |
Applications: | ICC |
Applications: | AC |
Reactivity: | Human, Mouse |
Details: | Rabbit IgG Polyclonal |
Applications: | WB, Simple Western |
Reactivity: | Human |
Details: | Mouse IgG2b Monoclonal Clone #115603 |
Applications: | ICFlow |
Reactivity: | Human, Mouse |
Details: | Mouse IgG2b Kappa Monoclonal Clone #19N12A1 |
Applications: | WB, Flow, Simple Western |
Reactivity: | Human |
Details: | Mouse IgG2b Monoclonal Clone #115603 |
Applications: | ICFlow |
Reactivity: | Human |
Details: | Mouse IgG2b Monoclonal Clone #115603 |
Applications: | ICFlow |