HMGB1/HMG-1 Products
HMGB1 (high-mobility group box 1 protein), also known as HMG1 or Amphoterin, is an intracellular protein that is regulated by multiple posttranslational modifications including acetylation, phosphorylation, and methylation. HMGB1 is released upon cell necrosis, apoptosis, and pyroptosis. It acts as a multifunctional alarmin that stimulates inflammation upon sterile or infectious insult. Receptors for HMGB1 include TLR2, TLR4, TLR9, Syndecan-3, Siglec-10, Integrin alpha M beta 2, CXCR4, TIM-3, and RAGE. It is implicated in the pathogenesis of a broad range of diseases including atherosclerosis, sepsis, cancer, neurodegenerative diseases, and autoimmunity.
Products:
215 results for "HMGB1/HMG-1" in Products
215 results for "HMGB1/HMG-1" in Products
HMGB1/HMG-1 Products
HMGB1 (high-mobility group box 1 protein), also known as HMG1 or Amphoterin, is an intracellular protein that is regulated by multiple posttranslational modifications including acetylation, phosphorylation, and methylation. HMGB1 is released upon cell necrosis, apoptosis, and pyroptosis. It acts as a multifunctional alarmin that stimulates inflammation upon sterile or infectious insult. Receptors for HMGB1 include TLR2, TLR4, TLR9, Syndecan-3, Siglec-10, Integrin alpha M beta 2, CXCR4, TIM-3, and RAGE. It is implicated in the pathogenesis of a broad range of diseases including atherosclerosis, sepsis, cancer, neurodegenerative diseases, and autoimmunity.
Products:
| Source: | NS0 |
| Accession #: | P09429 |
| Applications: | BA |
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #115603 |
| Applications: | WB, IHC, ChIP, CyTOF-ready, ICC, +1 More |
| Applications: | ELISA |
| Reactivity: | Human, Mouse, Rat, Canine, Bovine, +2 More |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ELISA, ICC/IF, Flow, +3 More |
![Knockdown Validated: HMGB1/HMG-1 Antibody [NB100-2322]](https://resources.bio-techne.com/images/products/HMGB1-HMG-1-Antibody-Knockdown-Validated-NB100-2322-img0025.jpg "Knockdown Validated: HMGB1/HMG-1 Antibody [NB100-2322]")
| Reactivity: | Human, E. coli |
| Details: | Mouse IgG2a Kappa Monoclonal Clone #2F6 |
| Applications: | IHC, WB, ELISA, ICC/IF, Func, +2 More |
![Western Blot: HMGB1/HMG-1 Antibody (2F6) [H00003146-M08]](https://resources.bio-techne.com/images/products/HMGB1-HMG-1-Antibody-2F6-Western-Blot-H00003146-M08-img0017.jpg "Western Blot: HMGB1/HMG-1 Antibody (2F6) [H00003146-M08]")
| Applications: | ELISA |
| Reactivity: | Human, Mouse |
| Details: | Mouse IgG2b Kappa Monoclonal Clone #19N10B7 |
| Applications: | IHC, WB, Flow, IP, CyTOF-ready, +2 More |
![Western Blot: HMGB1/HMG-1 Antibody (19N10B7)BSA Free [NBP2-27396]](https://resources.bio-techne.com/images/products/HMGB1-HMG-1-Antibody-19N10B7-Western-Blot-NBP2-27396-img0034.jpg "Western Blot: HMGB1/HMG-1 Antibody (19N10B7)BSA Free [NBP2-27396]")
| Reactivity: | Human, Mouse, Rat |
| Details: | Rat IgG2b Monoclonal Clone #951420 |
| Applications: | WB, Simple Western, IHC |
| Reactivity: | Human, Mouse |
| Details: | Chicken IgY Polyclonal |
| Applications: | WB, KO |
| Reactivity: | Human, Rat |
| Details: | Mouse IgG2a Kappa Monoclonal Clone #1D5 |
| Applications: | IHC, WB, ELISA, ICC/IF, MA |
![Western Blot: HMGB1/HMG-1 Antibody (1D5) [H00003146-M02]](https://resources.bio-techne.com/images/products/HMGB1-HMG-1-Antibody-1D5-Western-Blot-H00003146-M02-img0015.jpg "Western Blot: HMGB1/HMG-1 Antibody (1D5) [H00003146-M02]")
| Reactivity: | Human, Mouse |
| Details: | Mouse IgG2b Monoclonal Clone #1002147 |
| Applications: | ICC |
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #115603 |
| Applications: | ICFlow |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG2B Monoclonal Clone #1F3 |
| Applications: | IHC, WB, ICC/IF, Flow, CyTOF-ready, +2 More |
![Western Blot: HMGB1/HMG-1 Antibody (1F3) [NBP2-25148]](https://resources.bio-techne.com/images/products/HMGB1-HMG-1-Antibody-1F3-Western-Blot-NBP2-25148-img0009.jpg "Western Blot: HMGB1/HMG-1 Antibody (1F3) [NBP2-25148]")
| Reactivity: | Human, Mouse |
| Details: | Mouse IgG1 kappa Monoclonal Clone #19N15F4 |
| Applications: | IHC, WB, Flow |
![Western Blot: HMGB1/HMG-1 Antibody (19N15F4) [NBP2-27401]](https://resources.bio-techne.com/images/products/HMGB1-HMG-1-Antibody-19N15F4-Western-Blot-NBP2-27401-img0026.jpg "Western Blot: HMGB1/HMG-1 Antibody (19N15F4) [NBP2-27401]")
| Applications: | ELISA |
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, Flow, Simple Western |
![Western Blot: HMGB1/HMG-1 Antibody [NBP2-27117]](https://resources.bio-techne.com/images/products/HMGB1-HMG-1-Antibody-Western-Blot-NBP2-27117-img0008.jpg "Western Blot: HMGB1/HMG-1 Antibody [NBP2-27117]")
Recombinant Monoclonal Antibody
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #1C4T5 |
| Applications: | IHC, WB, ICC/IF, KO |
![Western Blot: HMGB1/HMG-1 Antibody (1C4T5) [NBP3-15755]](https://resources.bio-techne.com/images/products/HMGB1-HMG-1-Antibody-1C4T5-Western-Blot-NBP3-15755-img0007.jpg "Western Blot: HMGB1/HMG-1 Antibody (1C4T5) [NBP3-15755]")
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #115603 |
| Applications: | ICFlow |
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #115603 |
| Applications: | ICFlow |
| Applications: | AC |
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #115603 |
| Applications: | ICFlow |
| Reactivity: | Human, Mouse |
| Details: | Mouse IgG2b Kappa Monoclonal Clone #19N12A1 |
| Applications: | WB, Flow, Simple Western |
![Western Blot: HMGB1/HMG-1 Antibody (19N12A1) [NBP2-27400]](https://resources.bio-techne.com/images/products/HMGB1-HMG-1-Antibody-19N12A1-Western-Blot-NBP2-27400-img0004.jpg "Western Blot: HMGB1/HMG-1 Antibody (19N12A1) [NBP2-27400]")
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ELISA, ICC/IF |
![Western Blot: HMGB1/HMG-1 AntibodyBSA Free [NBP2-41264]](https://resources.bio-techne.com/images/products/HMGB1-HMG-1-Antibody-Western-Blot-NBP2-41264-img0001.jpg "Western Blot: HMGB1/HMG-1 AntibodyBSA Free [NBP2-41264]")
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #115603 |
| Applications: | ICFlow |
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, Simple Western |
![Western Blot: HMGB1/HMG-1 Antibody [NBP2-27169]](https://resources.bio-techne.com/images/products/HMGB1-HMG-1-Antibody-Western-Blot-NBP2-27169-img0003.jpg "Western Blot: HMGB1/HMG-1 Antibody [NBP2-27169]")