ICAM-1/CD54 Products
ICAM-1 (intercellular adhesion molecule-1), also known as CD54, is a transmembrane protein that is upregulated on endothelial and epithelial cells at sites of inflammation. It mediates the vascular adhesion and paracellular migration of leukocytes expressing activated LFA-1 (CD11a/CD18) and Mac-1 (CD11b/CD18). It also binds several non-integrin ligands including CD43/Sialophorin, Fibrinogen, Hyaluronan, rhinoviruses, and Plasmodium falciparum-infected erythrocytes. Soluble ICAM-1 promotes angiogenesis and serves an indicator of vascular endothelial cell activation or damage. Elevated levels of soluble ICAM-1 are associated with cardiovascular disease, type 2 diabetes, organ transplant dysfunction, oxidant stress, increased abdominal fat mass, hypertension, liver disease, certain malignancies, and cerebral malaria.
298 results for "ICAM-1/CD54" in Products
298 results for "ICAM-1/CD54" in Products
ICAM-1/CD54 Products
ICAM-1 (intercellular adhesion molecule-1), also known as CD54, is a transmembrane protein that is upregulated on endothelial and epithelial cells at sites of inflammation. It mediates the vascular adhesion and paracellular migration of leukocytes expressing activated LFA-1 (CD11a/CD18) and Mac-1 (CD11b/CD18). It also binds several non-integrin ligands including CD43/Sialophorin, Fibrinogen, Hyaluronan, rhinoviruses, and Plasmodium falciparum-infected erythrocytes. Soluble ICAM-1 promotes angiogenesis and serves an indicator of vascular endothelial cell activation or damage. Elevated levels of soluble ICAM-1 are associated with cardiovascular disease, type 2 diabetes, organ transplant dysfunction, oxidant stress, increased abdominal fat mass, hypertension, liver disease, certain malignancies, and cerebral malaria.
| Reactivity: | Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IHC, AdBlk |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #BBIG-I1 (11C81) |
| Applications: | WB, Flow, IP, AdBlk, ICC |
| Sensitivity: | 0.254 ng/mL |
| Applications: | ELISA |
| Assay Range: | 1.56 - 50 ng/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma) |
| Source: | NS0 |
| Accession #: | CAA30051 |
| Applications: | BA |
| Source: | NS0 |
| Accession #: | Q3U8M7 |
| Applications: | BA |
