IL-17/IL-17A: Proteins and Enzymes
IL-17/IL-17A is a homodimeric cytokine that is secreted by IL-23 activated Th17 and Tc17 cells. It is upregulated during inflammation and contributes to disease severity by enhancing neutrophil infiltration and the production of pro-inflammatory chemokines. IL-17A can additionally form bioactive heterodimers with IL-17F. IL-17A and the IL-17A/F heterodimer signal through widely expressed receptor complexes containing IL-17 RA and IL-17 RC.
2 results for "IL-17/IL-17A Proteins and Enzymes" in Products
2 results for "IL-17/IL-17A Proteins and Enzymes" in Products
IL-17/IL-17A: Proteins and Enzymes
IL-17/IL-17A is a homodimeric cytokine that is secreted by IL-23 activated Th17 and Tc17 cells. It is upregulated during inflammation and contributes to disease severity by enhancing neutrophil infiltration and the production of pro-inflammatory chemokines. IL-17A can additionally form bioactive heterodimers with IL-17F. IL-17A and the IL-17A/F heterodimer signal through widely expressed receptor complexes containing IL-17 RA and IL-17 RC.
| Source: | CHO |
| Accession #: | NP_001100367 |
| Applications: | BA |
| Applications: | Bioactivity, PAGE |