IL-17/IL-17A Products
IL-17/IL-17A is a homodimeric cytokine that is secreted by IL-23 activated Th17 and Tc17 cells. It is upregulated during inflammation and contributes to disease severity by enhancing neutrophil infiltration and the production of pro-inflammatory chemokines. IL-17A can additionally form bioactive heterodimers with IL-17F. IL-17A and the IL-17A/F heterodimer signal through widely expressed receptor complexes containing IL-17 RA and IL-17 RC.
3 results for "IL-17/IL-17A" in Products
3 results for "IL-17/IL-17A" in Products
IL-17/IL-17A Products
IL-17/IL-17A is a homodimeric cytokine that is secreted by IL-23 activated Th17 and Tc17 cells. It is upregulated during inflammation and contributes to disease severity by enhancing neutrophil infiltration and the production of pro-inflammatory chemokines. IL-17A can additionally form bioactive heterodimers with IL-17F. IL-17A and the IL-17A/F heterodimer signal through widely expressed receptor complexes containing IL-17 RA and IL-17 RC.
Reactivity: | Human |
Details: | Goat IgG Polyclonal |
Applications: | WB, IHC, IP, CyTOF-ready, ICC, +2 More |
Reactivity: | Human, Mouse, Rhesus Macaque, Primate - Macaca mulatta (Rhesus Macaque) |
Details: | Rabbit IgG Polyclonal |
Applications: | IHC, WB, ICC/IF, ELISA |
Reactivity: | Mouse |
Details: | Goat IgG Polyclonal |
Applications: | WB, CyTOF-ready, ICFlow, Neut |