IL-17/IL-17A Products
IL-17/IL-17A is a homodimeric cytokine that is secreted by IL-23 activated Th17 and Tc17 cells. It is upregulated during inflammation and contributes to disease severity by enhancing neutrophil infiltration and the production of pro-inflammatory chemokines. IL-17A can additionally form bioactive heterodimers with IL-17F. IL-17A and the IL-17A/F heterodimer signal through widely expressed receptor complexes containing IL-17 RA and IL-17 RC.
5 results for "IL-17/IL-17A" in Products
5 results for "IL-17/IL-17A" in Products
IL-17/IL-17A Products
IL-17/IL-17A is a homodimeric cytokine that is secreted by IL-23 activated Th17 and Tc17 cells. It is upregulated during inflammation and contributes to disease severity by enhancing neutrophil infiltration and the production of pro-inflammatory chemokines. IL-17A can additionally form bioactive heterodimers with IL-17F. IL-17A and the IL-17A/F heterodimer signal through widely expressed receptor complexes containing IL-17 RA and IL-17 RC.
Reactivity: | Human, Mouse, Rhesus Macaque, Primate - Macaca mulatta (Rhesus Macaque) |
Details: | Rabbit IgG Polyclonal |
Applications: | IHC, WB, ICC/IF, ELISA |
Assay Range: | 62.5 - 4,000 pg/mL |
Applications: | ELISA |
Reactivity: | Canine |
Details: | Mouse IgG2a Monoclonal Clone #665909 |
Applications: | Neut |
Source: | E. coli |
Accession #: | XP_538958.2 |
Applications: | BA |