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IL-27 Products

IL-27 is a heterodimeric cytokine that is composed of EBI3 (which is related to the p40 subunit of IL-12 and IL-23) and p28 (which is related to the p35 chain of IL-12). IL-27 is expressed by monocytes, endothelial cells, and dendritic cells. It signals through a receptor complex composed of IL-27 R alpha/WSX-1/TCCR and gp130. IL-27 induces IL-12 receptor expression on naïve CD4+ T cells, sensitizing them to subsequent IL-12-induced Th1 development. It also functions as an anti-inflammatory cytokine by limiting T and NKT cell activity.

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157 results for "IL-27" in Products

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157 results for "IL-27" in Products

IL-27 Products

IL-27 is a heterodimeric cytokine that is composed of EBI3 (which is related to the p40 subunit of IL-12 and IL-23) and p28 (which is related to the p35 chain of IL-12). IL-27 is expressed by monocytes, endothelial cells, and dendritic cells. It signals through a receptor complex composed of IL-27 R alpha/WSX-1/TCCR and gp130. IL-27 induces IL-12 receptor expression on naïve CD4+ T cells, sensitizing them to subsequent IL-12-induced Th1 development. It also functions as an anti-inflammatory cytokine by limiting T and NKT cell activity.

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His-tag

Contains 4 membranes - each spotted in duplicate with 40 different cytokine antibodies

Contains 4 membranes - each spotted in duplicate with 105 different cytokine antibodies

Applications: WB, Neut
Reactivity: Human
Applications: WB
Reactivity: Human
Applications: CyTOF-ready, ICFlow
Reactivity: Mouse
Applications: CyTOF-ready, ICFlow
Reactivity: Human
Applications: BA
Applications: BA
Applications: ICFlow
Reactivity: Mouse
Applications: WB, ICC/IF
Reactivity: Human, Mouse
Applications: ICFlow
Reactivity: Mouse
Applications: ICFlow
Reactivity: Mouse
Applications: ICFlow
Reactivity: Human
Applications: ICFlow
Reactivity: Mouse
Applications: BA

Biotinylated

Applications: ICFlow
Reactivity: Human
Applications: ICFlow
Reactivity: Human
Applications: ICFlow
Reactivity: Mouse
Applications: ICFlow
Reactivity: Human
Applications: ICFlow
Reactivity: Mouse
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