IL-4 Products
IL-4 (Interleukin-4) is a cytokine that is primarily expressed by Th2-biased CD4+ T cells, mast cells, basophils, and eosinophils. It promotes cell proliferation, survival, and immunoglobulin class switch to IgG4 and IgE in human B cells, acquisition of the Th2 phenotype by naïve CD4+ T cells, priming and chemotaxis of mast cells, eosinophils, and basophils, and the proliferation and activation of epithelial cells. IL-4 plays a dominant role in the development of allergic inflammation and asthma. The type I receptor for IL-4, which is expressed on hematopoietic cells, is a heterodimer of the ligand binding IL-4 R alpha and the common gamma chain (a shared subunit of the receptors for IL-2, -7, -9, -15, and -21). The type II receptor on nonhematopoietic cells consists of IL-4 R alpha and IL-13 R alpha 1. The type II receptor also transduces IL-13 mediated signals.
332 results for "IL-4" in Products
332 results for "IL-4" in Products
IL-4 Products
IL-4 (Interleukin-4) is a cytokine that is primarily expressed by Th2-biased CD4+ T cells, mast cells, basophils, and eosinophils. It promotes cell proliferation, survival, and immunoglobulin class switch to IgG4 and IgE in human B cells, acquisition of the Th2 phenotype by naïve CD4+ T cells, priming and chemotaxis of mast cells, eosinophils, and basophils, and the proliferation and activation of epithelial cells. IL-4 plays a dominant role in the development of allergic inflammation and asthma. The type I receptor for IL-4, which is expressed on hematopoietic cells, is a heterodimer of the ligand binding IL-4 R alpha and the common gamma chain (a shared subunit of the receptors for IL-2, -7, -9, -15, and -21). The type II receptor on nonhematopoietic cells consists of IL-4 R alpha and IL-13 R alpha 1. The type II receptor also transduces IL-13 mediated signals.
| Source: | E. coli |
| Accession #: | P07750 |
| Applications: | BA |
Analyzed by SEC-MALS
| Source: | E. coli |
| Accession #: | P05112.1 |
| Applications: | BA |
Intended for preclinical researchers who may transition to GMP IL-4 for their clinical work
| Source: | E. coli |
| Accession #: | P05112.1 |
| Applications: | BA |
| Source: | E. coli |
| Accession #: | P05112.1 |
| Applications: | BA |
| Source: | CHO |
| Accession #: | P05112 |
| Applications: | BA |
| Sensitivity: | 2 pg/mL |
| Applications: | ELISA |
| Assay Range: | 7.8 - 500 pg/mL (Cell Culture Supernates, Serum) |
| Assay Range: | 15.6 - 1,000 pg/mL |
| Applications: | ELISA |
| Sensitivity: | 10 pg/mL |
| Applications: | ELISA |
| Assay Range: | 31.2 - 2,000 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma, Citrate Plasma) |
| Assay Range: | 31.2 - 2,000 pg/mL |
| Applications: | ELISA |
Contains 4 membranes - each spotted in duplicate with 40 different cytokine antibodies
Luminex High Performance Assays go through rigorous development, validation, and quality control testing to ensure you are getting the best performance out of your multiplex assay. Panels are customizable so you can order a selection of the analytes or the entire panel.
| Applications: | ELISA |
Luminex High Performance Assays go through rigorous development, validation, and quality control testing to ensure you are getting the best performance out of your multiplex assay. Panels are customizable so you can order a selection of the analytes or the entire panel.
| Applications: | ELISA |
Contains 4 membranes - each spotted in duplicate with 36 different cytokine antibodies
| Reactivity: | Mouse |
| Details: | Rat IgG1 Monoclonal Clone #30340 |
| Applications: | WB, Neut |
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #34019 |
| Applications: | WB, Neut |
| Sensitivity: | 0.22 pg/mL |
| Applications: | ELISA |
| Assay Range: | 0.25 - 16 pg/mL (Cell Culture Supernates, Serum) |
Contains 4 membranes - each spotted in duplicate with 105 different cytokine antibodies
Contains 4 membranes-each spotted in duplicate with 111 different cytokine antibodies
Luminex High Performance Assays go through rigorous development, validation, and quality control testing to ensure you are getting the best performance out of your multiplex assay. Panels are customizable so you can order a selection of the analytes or the entire panel.
| Applications: | ELISA |
| Source: | E. coli |
| Accession #: | AAD11563 |
| Applications: | BA |
Luminex High Performance Assays go through rigorous development, validation, and quality control testing to ensure you are getting the best performance out of your multiplex assay. Panels are customizable so you can order a selection of the analytes or the entire panel.
| Applications: | ELISA |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #3007 |
| Applications: | WB, ICC, Neut |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, ICC |
Control for use with Human IL-4 2nd gen and Non-Human Primate IL-4 Simple Plex Cartridge Kit
| Applications: | Ctrl, Simple Plex |