IRAK1 Products
IL-1 receptor-associated kinases (IRAKs) are serine/threonine kinases that help mediate signaling from Toll-like receptor (TLR) and IL-1 receptor family members. Four human IRAKs have been identified: IRAK1, IRAK2, IRAK-M, and IRAK4. All IRAKs are multidomain proteins, containing a conserved N-terminal death domain as well as a central kinase domain that is only active in IRAK1 and IRAK4. IRAK4 mutations have been described in patients with recurrent bacterial infections and poor inflammatory responses.
48 results for "IRAK1" in Products
48 results for "IRAK1" in Products
IRAK1 Products
IL-1 receptor-associated kinases (IRAKs) are serine/threonine kinases that help mediate signaling from Toll-like receptor (TLR) and IL-1 receptor family members. Four human IRAKs have been identified: IRAK1, IRAK2, IRAK-M, and IRAK4. All IRAKs are multidomain proteins, containing a conserved N-terminal death domain as well as a central kinase domain that is only active in IRAK1 and IRAK4. IRAK4 mutations have been described in patients with recurrent bacterial infections and poor inflammatory responses.
IRAK4 and IRAK1 inhibitor
| Chemical Name: | N-[1-[2-(4-Morpholinyl)ethyl]-1H-benzimidazol-2-yl]-3-nitrobenzamide |
| Purity: | ≥98% (HPLC) |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, Simple Western |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ICC/IF, ELISA, IP, Func |
![Western Blot: IRAK1 AntibodyBSA Free [NBP1-77068]](https://resources.bio-techne.com/images/products/IRAK1-Antibody-Western-Blot-NBP1-77068-img0009.jpg "Western Blot: IRAK1 AntibodyBSA Free [NBP1-77068]")
| Reactivity: | Human |
| Details: | Mouse IgG1 kappa Monoclonal Clone #3A9 |
| Applications: | IHC, WB, ELISA, ICC/IF, IP, +1 More |
![Western Blot: IRAK1 Antibody (3A9) [H00003654-M02]](https://resources.bio-techne.com/images/products/IRAK1-Antibody-3A9-Western-Blot-H00003654-M02-img0022.jpg "Western Blot: IRAK1 Antibody (3A9) [H00003654-M02]")
| Reactivity: | Human |
| Details: | Mouse IgG2a Kappa Monoclonal Clone #3F7 |
| Applications: | IHC, WB, ELISA, ICC/IF, IP |
![Western Blot: IRAK1 Antibody (3F7) [H00003654-M01]](https://resources.bio-techne.com/images/products/IRAK1-Antibody-3F7-Western-Blot-H00003654-M01-img0015.jpg "Western Blot: IRAK1 Antibody (3F7) [H00003654-M01]")
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, IP |
![Western Blot: IRAK1 Antibody [NB100-56699]](https://resources.bio-techne.com/images/products/IRAK1-Antibody-Western-Blot-NB100-56699-img0003.jpg "Western Blot: IRAK1 Antibody [NB100-56699]")
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #SR2210 |
| Applications: | WB, ICC/IF, IP |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, ICC/IF |
![Immunocytochemistry/ Immunofluorescence: IRAK1 Antibody [NBP2-38726]](https://resources.bio-techne.com/images/products/IRAK1-Antibody-Immunocytochemistry-Immunofluorescence-NBP2-38726-img0003.jpg "Immunocytochemistry/ Immunofluorescence: IRAK1 Antibody [NBP2-38726]")
| Applications: | AC |
| Applications: | WB, ELISA, MA, AP, PAGE |
| Applications: | WB, ELISA, MA, AP |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #1H5U0 |
| Applications: | WB |
![Western Blot: IRAK1 Antibody (1H5U0) [NBP3-16415]](https://resources.bio-techne.com/images/products/IRAK1-Antibody-1H5U0-Western-Blot-NBP3-16415-img0001.jpg "Western Blot: IRAK1 Antibody (1H5U0) [NBP3-16415]")
| Applications: | WB |
![Western Blot: IRAK1 Overexpression Lysate [NBL1-12026]](https://resources.bio-techne.com/images/products/IRAK-Overexpression-Lysate-Adult-Normal-Western-Blot-NBL1-12026-img0002.jpg "Western Blot: IRAK1 Overexpression Lysate [NBL1-12026]")
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, IP |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, IP |
| Applications: | WB |
![Western Blot: IRAK1 Overexpression Lysate [NBL1-12025]](https://resources.bio-techne.com/images/products/IRAK-Overexpression-Lysate-Adult-Normal-Western-Blot-NBL1-12025-img0002.jpg "Western Blot: IRAK1 Overexpression Lysate [NBL1-12025]")
| Applications: | WB |
![Western Blot: IRAK1 Overexpression Lysate [NBP2-11046]](https://resources.bio-techne.com/images/products/IRAK-Overexpression-Lysate-Adult-Normal-Western-Blot-NBP2-11046-img0001.jpg "Western Blot: IRAK1 Overexpression Lysate [NBP2-11046]")
| Applications: | AC |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ELISA, ICC/IF, IP |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ELISA, ICC/IF, IP |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ELISA, ICC/IF, IP |
Contains 4 membranes-each spotted in duplicate with 41 different proteins and 4 serine or tyrosine phosphorylation sites antibodies
Negative control for the IRAK1 degrader JNJ 1013 (Cat. No. 8029)
| Chemical Name: | N-(4-(4-(2-(((S)-1-((2S,4S)-4-Hydroxy-2-(((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)carbamoyl)pyrrolidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl)amino)-2-oxoethoxy)piperidin-1-yl)-2-methoxyphenyl)-6-(1H-pyrazol-5-yl)picolinamide |
| Purity: | ≥95% (HPLC) |
