Kos1/Tnk1 Products
Kinase of embryonic stem cells (Kos1) is a nonreceptor protein tyrosine kinase (NRPTK) and a new member of the Ack family of NRPTKs. Kos1 is a ubiquitously expressed 47-kDa protein with autotyrosine kinase activity that is developmentally regulated during embryogenesis. Kos1 is also upregulated following IL3 withdrawal from factor-dependent murine NSF/N1.H7 cells that undergo apoptosis, suggesting a role in growth inhibition. Data support a negative regulatory role for Kos1 in regulating the Ras-Raf1-MAPK growth pathway by a mechanism that requires its autotyrosine kinase activity.
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33 results for "Kos1/Tnk1" in Products
33 results for "Kos1/Tnk1" in Products
Kos1/Tnk1 Products
Kinase of embryonic stem cells (Kos1) is a nonreceptor protein tyrosine kinase (NRPTK) and a new member of the Ack family of NRPTKs. Kos1 is a ubiquitously expressed 47-kDa protein with autotyrosine kinase activity that is developmentally regulated during embryogenesis. Kos1 is also upregulated following IL3 withdrawal from factor-dependent murine NSF/N1.H7 cells that undergo apoptosis, suggesting a role in growth inhibition. Data support a negative regulatory role for Kos1 in regulating the Ras-Raf1-MAPK growth pathway by a mechanism that requires its autotyrosine kinase activity.
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Reactivity: | Human, Mouse |
Details: | Rabbit IgG Polyclonal |
Applications: | WB, ICC/IF |
Applications: WB, ICC/IF
Reactivity:
Human,
Mouse
Reactivity: | Human, Mouse |
Details: | Rabbit IgG Polyclonal |
Applications: | WB, ICC/IF |
Applications: WB, ICC/IF
Reactivity:
Human,
Mouse
Reactivity: | Human, Mouse |
Details: | Rabbit IgG Polyclonal |
Applications: | WB, ICC/IF |
Applications: WB, ICC/IF
Reactivity:
Human,
Mouse
Reactivity: | Human, Mouse |
Details: | Rabbit IgG Polyclonal |
Applications: | WB, ICC/IF |
Applications: WB, ICC/IF
Reactivity:
Human,
Mouse
Reactivity: | Human, Mouse |
Details: | Rabbit IgG Polyclonal |
Applications: | WB, ICC/IF |
Applications: WB, ICC/IF
Reactivity:
Human,
Mouse
Reactivity: | Human, Mouse |
Details: | Rabbit IgG Polyclonal |
Applications: | WB, ICC/IF |
Applications: WB, ICC/IF
Reactivity:
Human,
Mouse
Reactivity: | Human, Mouse |
Details: | Rabbit IgG Polyclonal |
Applications: | WB, ICC/IF |
Applications: WB, ICC/IF
Reactivity:
Human,
Mouse
Reactivity: | Human, Mouse |
Details: | Rabbit IgG Polyclonal |
Applications: | WB, ICC/IF |
Applications: WB, ICC/IF
Reactivity:
Human,
Mouse
Reactivity: | Human, Mouse |
Details: | Rabbit IgG Polyclonal |
Applications: | WB, ICC/IF |
Applications: WB, ICC/IF
Reactivity:
Human,
Mouse
Reactivity: | Human, Mouse |
Details: | Rabbit IgG Polyclonal |
Applications: | WB, ICC/IF |
Applications: WB, ICC/IF
Reactivity:
Human,
Mouse
Reactivity: | Human, Mouse |
Details: | Rabbit IgG Polyclonal |
Applications: | WB, ICC/IF |
Applications: WB, ICC/IF
Reactivity:
Human,
Mouse
Reactivity: | Human, Mouse |
Details: | Rabbit IgG Polyclonal |
Applications: | WB, ICC/IF |
Applications: WB, ICC/IF
Reactivity:
Human,
Mouse
Reactivity: | Human, Mouse |
Details: | Rabbit IgG Polyclonal |
Applications: | WB, ICC/IF |
Applications: WB, ICC/IF
Reactivity:
Human,
Mouse
Reactivity: | Human, Mouse |
Details: | Rabbit IgG Polyclonal |
Applications: | WB, ICC/IF |
Applications: WB, ICC/IF
Reactivity:
Human,
Mouse
Reactivity: | Human, Mouse |
Details: | Rabbit IgG Polyclonal |
Applications: | WB, ICC/IF |
Applications: WB, ICC/IF
Reactivity:
Human,
Mouse
Reactivity: | Human, Mouse |
Details: | Rabbit IgG Polyclonal |
Applications: | WB, ICC/IF |
Applications: WB, ICC/IF
Reactivity:
Human,
Mouse
Reactivity: | Human, Mouse |
Details: | Rabbit IgG Polyclonal |
Applications: | WB, ICC/IF |
Applications: WB, ICC/IF
Reactivity:
Human,
Mouse
Reactivity: | Human, Mouse |
Details: | Rabbit IgG Polyclonal |
Applications: | WB, ICC/IF |
Applications: WB, ICC/IF
Reactivity:
Human,
Mouse
Reactivity: | Human, Mouse |
Details: | Rabbit IgG Polyclonal |
Applications: | WB, ICC/IF |
Applications: WB, ICC/IF
Reactivity:
Human,
Mouse
Reactivity: | Human, Mouse |
Details: | Rabbit IgG Polyclonal |
Applications: | WB, ICC/IF |
Applications: WB, ICC/IF
Reactivity:
Human,
Mouse
Reactivity: | Human, Mouse |
Details: | Rabbit IgG Polyclonal |
Applications: | WB, ICC/IF |
Applications: WB, ICC/IF
Reactivity:
Human,
Mouse
Reactivity: | Human, Mouse |
Details: | Rabbit IgG Polyclonal |
Applications: | WB, ICC/IF |
Applications: WB, ICC/IF
Reactivity:
Human,
Mouse
Reactivity: | Human, Mouse |
Details: | Rabbit IgG Polyclonal |
Applications: | WB, ICC/IF |
Applications: WB, ICC/IF
Reactivity:
Human,
Mouse
Reactivity: | Human, Mouse |
Details: | Rabbit IgG Polyclonal |
Applications: | WB, ICC/IF |
Applications: WB, ICC/IF
Reactivity:
Human,
Mouse
Reactivity: | Human, Mouse |
Details: | Rabbit IgG Polyclonal |
Applications: | WB, ICC/IF |