LAT Products
LAT (Linker for Activation of T cells) is a type III transmembrane lipid raft protein that serves as a scaffold for signaling molecules. Upon T-cell antigen receptor activation, LAT is multiply phosphorylated by ZAP-70/Syk protein tyrosine kinases, creating docking sites for SH2 domain-containing proteins. For example, phospholipase C-gamma docks at Y161, which is pY132 in the short form. Mutation of this site results in a Th2 autoimmune lymphoproliferative disorder in mice.
71 results for "LAT" in Products
71 results for "LAT" in Products
LAT Products
LAT (Linker for Activation of T cells) is a type III transmembrane lipid raft protein that serves as a scaffold for signaling molecules. Upon T-cell antigen receptor activation, LAT is multiply phosphorylated by ZAP-70/Syk protein tyrosine kinases, creating docking sites for SH2 domain-containing proteins. For example, phospholipase C-gamma docks at Y161, which is pY132 in the short form. Mutation of this site results in a Th2 autoimmune lymphoproliferative disorder in mice.
| Reactivity: | Human |
| Details: | Mouse IgG1 kappa Monoclonal Clone #LAT.10-17 |
| Applications: | IHC, WB, Flow, IP |
![Western Blot: LAT Antibody (LAT.10-17)BSA Free [NBP2-00289]](https://resources.bio-techne.com/images/products/LAT-Antibody-LAT-10-17-Western-Blot-NBP2-00289-img0001.jpg "Western Blot: LAT Antibody (LAT.10-17)BSA Free [NBP2-00289]")
| Reactivity: | Human |
| Details: | Mouse IgG1 kappa Monoclonal Clone #LAT.10-17 |
| Applications: | IHC, WB, Flow, IP |
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #661002 |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Sheep IgG Polyclonal |
| Applications: | WB |
Recombinant Monoclonal Antibody
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #SR1644 |
| Applications: | IHC, WB, ICC/IF, IP |
| Reactivity: | Human, Mouse, Primate |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB |
![Western Blot: LAT Antibody [NBP2-27104]](https://resources.bio-techne.com/images/products/LAT-Antibody-Western-Blot-NBP2-27104-img0001.jpg "Western Blot: LAT Antibody [NBP2-27104]")
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #627945 |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF |
![Western Blot: LAT Antibody [NBP1-81324]](https://resources.bio-techne.com/images/products/LAT-Antibody-Western-Blot-NBP1-81324-img0006.jpg "Western Blot: LAT Antibody [NBP1-81324]")
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #2E4 |
| Applications: | IHC, WB, ELISA, ICC/IF, IP |
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB |
![Western Blot: LAT [p Tyr191] AntibodyAzide and BSA Free [NBP3-16940]](https://resources.bio-techne.com/images/products/LAT-[p-Tyr191]-Antibody-Western-Blot-NBP3-16940-img0001.jpg "Western Blot: LAT [p Tyr191] AntibodyAzide and BSA Free [NBP3-16940]")
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #SR1593 |
| Applications: | IHC, WB |
| Reactivity: | Human, Mouse, Rat |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, ELISA |
![Western Blot: LAT Antibody [NB100-1441]](https://resources.bio-techne.com/images/products/LAT-Antibody-Western-Blot-NB100-1441-img0002.jpg "Western Blot: LAT Antibody [NB100-1441]")
| Applications: | WB |
![Western Blot: LAT Overexpression Lysate [NBP2-09156]](https://resources.bio-techne.com/images/products/LAT-Overexpression-Lysate-Adult-Normal-Western-Blot-NBP2-09156-img0001.jpg "Western Blot: LAT Overexpression Lysate [NBP2-09156]")
| Applications: | ELISA |
| Applications: | PAGE |
![SDS-PAGE: Recombinant Human LAT His Protein [NBP1-72479]](https://resources.bio-techne.com/images/products/Recombinant-Human-LAT-Protein-SDS-Page-NBP1-72479-img0001.jpg "SDS-PAGE: Recombinant Human LAT His Protein [NBP1-72479]")
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, IP |
| Applications: | AC |
| Reactivity: | Human |
| Details: | Mouse IgG2B Monoclonal Clone #661002 |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Mouse IgG1 kappa Monoclonal Clone #LAT.10-17 |
| Applications: | IHC, WB, Flow, IP |
| Reactivity: | Human |
| Details: | Mouse IgG1 kappa Monoclonal Clone #LAT.10-17 |
| Applications: | IHC, WB, Flow, IP |
| Reactivity: | Human |
| Details: | Mouse IgG1 kappa Monoclonal Clone #LAT.10-17 |
| Applications: | IHC, WB, Flow, IP |
| Reactivity: | Human |
| Details: | Mouse IgG1 kappa Monoclonal Clone #LAT.10-17 |
| Applications: | IHC, WB, Flow, IP |
| Reactivity: | Human |
| Details: | Mouse IgG1 kappa Monoclonal Clone #LAT.10-17 |
| Applications: | IHC, WB, Flow, IP |
| Reactivity: | Human |
| Details: | Mouse IgG1 kappa Monoclonal Clone #LAT.10-17 |
| Applications: | Flow |