LIGHT/TNFSF14 Products
LIGHT, also known as TNFSF14, is a homotrimeric glycoprotein in the TNF superfamily. It is expressed on the surface of activated lymphocytes, NK cells, immature dendritic cells, monocytes, and granulocytes. A soluble form can be shed by proteolysis. LIGHT binds and activates HVEM/TNFRSF14 to costimulate Th1 immune responses, enhance CD8+ T cell‑mediated tumor immunity, and regulate allogeneic T cell activation and allograft rejection. In addition, it binds and activates Lymphotoxin beta R/TNFRSF3 to induce apoptosis, cytokine production, mesenteric lymph node organogenesis, and maintenance of lymph node structure and function. It can also bind the soluble human decoy receptor DcR3/TNFRSF6B.
Products:
108 results for "LIGHT/TNFSF14" in Products
108 results for "LIGHT/TNFSF14" in Products
LIGHT/TNFSF14 Products
LIGHT, also known as TNFSF14, is a homotrimeric glycoprotein in the TNF superfamily. It is expressed on the surface of activated lymphocytes, NK cells, immature dendritic cells, monocytes, and granulocytes. A soluble form can be shed by proteolysis. LIGHT binds and activates HVEM/TNFRSF14 to costimulate Th1 immune responses, enhance CD8+ T cell‑mediated tumor immunity, and regulate allogeneic T cell activation and allograft rejection. In addition, it binds and activates Lymphotoxin beta R/TNFRSF3 to induce apoptosis, cytokine production, mesenteric lymph node organogenesis, and maintenance of lymph node structure and function. It can also bind the soluble human decoy receptor DcR3/TNFRSF6B.
Products:
| Reactivity: | Human, Rat |
| Details: | Mouse IgG1 kappa Monoclonal Clone #C1 |
| Applications: | WB |
| Applications: | AC |
| Applications: | WB |
![Western Blot: LIGHT/TNFSF14 Overexpression Lysate [NBP2-07946]](https://resources.bio-techne.com/images/products/TNFSF14-Overexpression-Lysate-Adult-Normal-Western-Blot-NBP2-07946-img0001.jpg "Western Blot: LIGHT/TNFSF14 Overexpression Lysate [NBP2-07946]")
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Human IgG1 Monoclonal Clone #SAR252067 |
| Applications: | ELISA, Flow, Func |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Human IgG1 Monoclonal Clone #SAR252067 |
| Applications: | ELISA, Flow, Func |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Human IgG1 Monoclonal Clone #SAR252067 |
| Applications: | ELISA, Flow, Func |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Human IgG1 Monoclonal Clone #SAR252067 |
| Applications: | ELISA, Flow, Func |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #MM0456-8C34 |
| Applications: | Flow, CyTOF-ready |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Human IgG1 Monoclonal Clone #SAR252067 |
| Applications: | ELISA, Flow, Func |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #115520 |
| Applications: | ELISA, Flow, CyTOF-ready, ELISA(Cap), ELISA(Det) |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #115520 |
| Applications: | ELISA, Flow, CyTOF-ready, ELISA(Cap), ELISA(Det) |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Human IgG1 Monoclonal Clone #SAR252067 |
| Applications: | ELISA, Flow, Func |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #115520 |
| Applications: | ELISA, Flow, CyTOF-ready, ELISA(Cap), ELISA(Det) |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #115520 |
| Applications: | ELISA, Flow, CyTOF-ready, ELISA(Cap), ELISA(Det) |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #MM0456-8C34 |
| Applications: | Flow, CyTOF-ready |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #115520 |
| Applications: | ELISA, Flow, CyTOF-ready, ELISA(Cap), ELISA(Det) |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #MM0456-8C34 |
| Applications: | Flow, CyTOF-ready |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #115520 |
| Applications: | ELISA, Flow, CyTOF-ready, ELISA(Cap), ELISA(Det) |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #MM0456-8C34 |
| Applications: | Flow, CyTOF-ready |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Human IgG1 Monoclonal Clone #SAR252067 |
| Applications: | ELISA, Flow, Func |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Human IgG1 Monoclonal Clone #SAR252067 |
| Applications: | ELISA, Flow, Func |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Human IgG1 Monoclonal Clone #SAR252067 |
| Applications: | ELISA, Flow, Func |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #MM0456-8C34 |
| Applications: | Flow, CyTOF-ready |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #115520 |
| Applications: | ELISA, Flow, CyTOF-ready, ELISA(Cap), ELISA(Det) |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #MM0456-8C34 |
| Applications: | Flow, CyTOF-ready |