Lymphotoxin-alpha/TNF-beta Products
TNF-beta, also known as lymphotoxin-alpha (LTalpha) and TNF-alpha are two structurally and functionally related proteins that bind to the same cell surface receptors (TNF RI and TNF RII) and produce a vast range of similar, but not identical effects. Mature TNF-beta/LTalpha and TNF-alpha share approximately 35% protein sequence homology, and the biologically active secreted forms of both proteins are trimers. Human and mouse TNF-beta/LTalpha share approximately 74% homology in their amino acid sequence and exhibit cross-species activity. Soluble TNF-beta/LTalpha is a homotrimer in solution. Secreted TNF-beta/LTalpha also complexes with the membrane associated LTbeta/TNFSF3 to generate two types of heterotrimers, LTalpha1/beta2 and LTalpha2/beta1.
160 results for "Lymphotoxin-alpha/TNF-beta" in Products
160 results for "Lymphotoxin-alpha/TNF-beta" in Products
Lymphotoxin-alpha/TNF-beta Products
TNF-beta, also known as lymphotoxin-alpha (LTalpha) and TNF-alpha are two structurally and functionally related proteins that bind to the same cell surface receptors (TNF RI and TNF RII) and produce a vast range of similar, but not identical effects. Mature TNF-beta/LTalpha and TNF-alpha share approximately 35% protein sequence homology, and the biologically active secreted forms of both proteins are trimers. Human and mouse TNF-beta/LTalpha share approximately 74% homology in their amino acid sequence and exhibit cross-species activity. Soluble TNF-beta/LTalpha is a homotrimer in solution. Secreted TNF-beta/LTalpha also complexes with the membrane associated LTbeta/TNFSF3 to generate two types of heterotrimers, LTalpha1/beta2 and LTalpha2/beta1.
Luminex High Performance Assays go through rigorous development, validation, and quality control testing to ensure you are getting the best performance out of your multiplex assay. Panels are customizable so you can order a selection of the analytes or the entire panel.
| Applications: | ELISA |
Defined heterotrimer stoichiometry
| Source: | HEK293 |
| Accession #: | P01374 (rhLT alpha ), Q06643 (rhLT beta ) & Q06643 (rhLT beta ) |
| Applications: | BA |
| Source: | E. coli |
| Accession #: | P01374 |
| Applications: | BA |
| Assay Range: | 31.2 - 2,000 pg/mL |
| Applications: | ELISA |
Luminex High Performance Assays go through rigorous development, validation, and quality control testing to ensure you are getting the best performance out of your multiplex assay. Panels are customizable so you can order a selection of the analytes or the entire panel.
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #5802 |
| Applications: | ICC, Neut |
| Reactivity: | Mouse |
| Details: | Rat IgG2b Monoclonal Clone #168717 |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, Neut |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, Neut |
| Reactivity: | Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
Recombinant Monoclonal Antibody.
| Reactivity: | Human |
| Details: | Mouse IgG2a Monoclonal Clone #5807R |
| Applications: | Neut |
| Reactivity: | Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IHC |
Biotinylated His-tag
| Source: | HEK293 |
| Accession #: | P01374 (alpha) & Q06643-1 (beta) |
| Applications: | BA |
| Applications: | ELISA |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB |
![Western Blot: Lymphotoxin-alpha/TNF-beta Antibody [NBP1-87725]](https://resources.bio-techne.com/images/products/Lymphotoxin-alpha-TNF-beta-Antibody-Western-Blot-NBP1-87725-img0007.jpg "Western Blot: Lymphotoxin-alpha/TNF-beta Antibody [NBP1-87725]")
| Applications: | ELISA |
![ELISA: Human Lymphotoxin-alpha/TNF-beta ELISA Kit (Colorimetric) [NBP1-83730]](https://resources.bio-techne.com/images/products/Human-Lymphotoxin-alpha-TNF-beta-ELISA-Kit-Colorimetric-ELISA-NBP1-83730-img0001.jpg "ELISA: Human Lymphotoxin-alpha/TNF-beta ELISA Kit (Colorimetric) [NBP1-83730]")
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Rabbit IgG Kappa Monoclonal Clone #3F12.2D3 |
| Applications: | WB, ELISA, Flow, B/N, SPR |
![Western Blot: Lymphotoxin-alpha/TNF-beta Antibody (3F12.2D3)ChimericAzide and BSA Free [NBP2-81105]](https://resources.bio-techne.com/images/products/Lymphotoxin-alpha-TNF-beta-Antibody-3F12-2D3-Chimeric-Western-Blot-NBP2-81105-img0002.jpg "Western Blot: Lymphotoxin-alpha/TNF-beta Antibody (3F12.2D3)ChimericAzide and BSA Free [NBP2-81105]")
| Applications: | AC |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Mouse IgG2b Kappa Monoclonal Clone #3F12.2D3 |
| Applications: | ELISA, Flow, B/N, SPR |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Rabbit IgG Kappa Monoclonal Clone #3F12.2D3 |
| Applications: | WB, ELISA, Flow, B/N, SPR |
| Applications: | ELISA |
Recombinant monoclonal antibody expressed in HEK293F cells
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #3G11 |
| Applications: | ELISA |