Lymphotoxin-alpha/TNF-beta Products
TNF-beta, also known as lymphotoxin-alpha (LTalpha) and TNF-alpha are two structurally and functionally related proteins that bind to the same cell surface receptors (TNF RI and TNF RII) and produce a vast range of similar, but not identical effects. Mature TNF-beta/LTalpha and TNF-alpha share approximately 35% protein sequence homology, and the biologically active secreted forms of both proteins are trimers. Human and mouse TNF-beta/LTalpha share approximately 74% homology in their amino acid sequence and exhibit cross-species activity. Soluble TNF-beta/LTalpha is a homotrimer in solution. Secreted TNF-beta/LTalpha also complexes with the membrane associated LTbeta/TNFSF3 to generate two types of heterotrimers, LTalpha1/beta2 and LTalpha2/beta1.
119 results for "Lymphotoxin-alpha/TNF-beta" in Products
119 results for "Lymphotoxin-alpha/TNF-beta" in Products
Lymphotoxin-alpha/TNF-beta Products
TNF-beta, also known as lymphotoxin-alpha (LTalpha) and TNF-alpha are two structurally and functionally related proteins that bind to the same cell surface receptors (TNF RI and TNF RII) and produce a vast range of similar, but not identical effects. Mature TNF-beta/LTalpha and TNF-alpha share approximately 35% protein sequence homology, and the biologically active secreted forms of both proteins are trimers. Human and mouse TNF-beta/LTalpha share approximately 74% homology in their amino acid sequence and exhibit cross-species activity. Soluble TNF-beta/LTalpha is a homotrimer in solution. Secreted TNF-beta/LTalpha also complexes with the membrane associated LTbeta/TNFSF3 to generate two types of heterotrimers, LTalpha1/beta2 and LTalpha2/beta1.
Luminex High Performance Assays go through rigorous development, validation, and quality control testing to ensure you are getting the best performance out of your multiplex assay. Panels are customizable so you can order a selection of the analytes or the entire panel.
Applications: | ELISA |
Defined heterotrimer stoichiometry
Source: | HEK293 |
Accession #: | P01374 (rhLT alpha ), Q06643 (rhLT beta ) & Q06643 (rhLT beta ) |
Applications: | BA |
Source: | E. coli |
Accession #: | P01374 |
Applications: | BA |
Defined heterotrimer stoichiometry
Source: | HEK293 |
Accession #: | P01374 (rhLT alpha ), Q06643 (rhLT beta ) & Q06643 (rhLT beta ) |
Applications: | BA |
Reactivity: | Human |
Details: | Goat IgG Polyclonal |
Applications: | WB, Neut |
Recombinant Monoclonal Antibody.
Reactivity: | Human |
Details: | Mouse IgG2a Monoclonal Clone #5807R |
Applications: | Neut |
Reactivity: | Mouse |
Details: | Goat IgG Polyclonal |
Applications: | WB, IHC |
Reactivity: | Human |
Details: | Mouse IgG1 Monoclonal Clone #5802 |
Applications: | ICC, Neut |
Reactivity: | Human |
Details: | Goat IgG Polyclonal |
Applications: | WB |
Assay Range: | 31.2 - 2,000 pg/mL |
Applications: | ELISA |
Applications: | ELISA |
Reactivity: | Mouse |
Details: | Goat IgG Polyclonal |
Applications: | WB |
Reactivity: | Human |
Details: | Goat IgG Polyclonal |
Applications: | WB, Neut |
Reactivity: | Mouse |
Details: | Rat IgG2b Monoclonal Clone #168717 |
Applications: | WB |
Biotinylated His-tag
Source: | HEK293 |
Accession #: | P01374 (alpha) & Q06643-1 (beta) |
Applications: | BA |
Luminex High Performance Assays go through rigorous development, validation, and quality control testing to ensure you are getting the best performance out of your multiplex assay. Panels are customizable so you can order a selection of the analytes or the entire panel.
Reactivity: | Human |
Details: | Rabbit IgG Polyclonal |
Applications: | IHC, WB |
Applications: | ELISA |
Applications: | ELISA |
Applications: | ELISA |
Recombinant Monoclonal Antibody
Reactivity: | Human |
Details: | Rabbit IgG Kappa Monoclonal Clone #3F12.2D3 |
Applications: | WB, ELISA, Flow, B/N, SPR |
Recombinant Monoclonal Antibody
Reactivity: | Human |
Details: | Human IgG1 Monoclonal |
Applications: | ELISA, Flow, Func |
Recombinant Monoclonal Antibody
Reactivity: | Human |
Details: | Mouse IgG2b Kappa Monoclonal Clone #3F12.2D3 |
Applications: | ELISA, Flow, B/N, SPR |