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MMP-8 Products

The matrix metalloproteinases (MMPs) consist of 24 known human zinc proteases with essential roles in breaking down components of the extracellular matrix (ECM). Additional MMP substrates include cytokines, chemokines, growth factors and binding proteins, cell/cell adhesion molecules, and other proteinases. With a few exceptions, MMPs share common structural motifs including a pro-peptide domain, a catalytic domain, a hinge region, and a hemopexin-like domain. Synthesized as pro-enzymes, most MMPs are secreted before conversion to their active form. MMP activities are modulated on several levels including transcription, pro-enzyme activation, or by their endogenous inhibitors, tissue inhibitors of metalloproteinases (TIMPs). A subset of MMPs are associated with membranes and designated as membrane-type metalloproteinases (MT-MMP).

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170 results for "MMP-8" in Products

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170 results for "MMP-8" in Products

MMP-8 Products

The matrix metalloproteinases (MMPs) consist of 24 known human zinc proteases with essential roles in breaking down components of the extracellular matrix (ECM). Additional MMP substrates include cytokines, chemokines, growth factors and binding proteins, cell/cell adhesion molecules, and other proteinases. With a few exceptions, MMPs share common structural motifs including a pro-peptide domain, a catalytic domain, a hinge region, and a hemopexin-like domain. Synthesized as pro-enzymes, most MMPs are secreted before conversion to their active form. MMP activities are modulated on several levels including transcription, pro-enzyme activation, or by their endogenous inhibitors, tissue inhibitors of metalloproteinases (TIMPs). A subset of MMPs are associated with membranes and designated as membrane-type metalloproteinases (MT-MMP).

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Contains 4 membranes - each spotted in duplicate with 55 different angiogenesis antibodies

Applications: WB, IHC, IP, ICC
Reactivity: Human
Applications: ELISA, IHC, CyTOF-ready, ICFlow
Reactivity: Human
Applications: WB, IHC
Reactivity: Human
Applications: Simple Plex

Simple Plex Human Total MMP-8 assay kit for use on Ella instrument. Contains cartridge, Sample Diluent SD13, and wash buffer.

Applications: WB, IP
Reactivity: Human

Contains 4 membranes - each spotted in duplicate with 35 different protease antibodies

Contains 4 membranes-2 spotted in duplicate with antibodies against 35 different proteases and 2 spotted in duplicate with antibodies against 32 different protease inhibitors

Applications: WB, IP
Reactivity: Mouse, Rat
Applications: IHC
Reactivity: Human, Mouse, Rat

Recombinant Monoclonal Antibody

Applications: ICFlow
Reactivity: Human
Applications: ICFlow
Reactivity: Human
Applications: WB
Reactivity: Rat
Applications: EnzAct
Applications: IHC, ICC/IF
Reactivity: Human
Applications: Simple Plex

Control for use with Human Total MMP-8 Simple Plex Assay Cartridge Kit

Applications: IHC, WB, ICC/IF, Flow, IP
Reactivity: Human, Mouse, Rat

Recombinant Monoclonal Antibody

Applications: ELISA
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