Nicastrin Products
Nicastrin (NCT) is a 150 - 160 kDa member of the nicastrin family of proteins. It is a component of the aspartyl protease γ-secretase complex and serves to stabilize and direct γ-secretase components to proper positions in the plasma membrane. The γ-secretase complex mediates the cleavage of intramembrane proteins such as notch-1 and APP. Mature human nicastrin is a 676 amino acid type I transmembrane glycoprotein. It contains a 636 aa extracellular domain (aa 34 - 669) that shows a 58 aa sequence (aa 312 - 369) which interacts with γ-secretase substrates. There are multiple splice variants of nicastrin. Over aa 34 - 669, human nicastrin shares 90% aa identity with mouse nicastrin.
176 results for "Nicastrin" in Products
176 results for "Nicastrin" in Products
Nicastrin Products
Nicastrin (NCT) is a 150 - 160 kDa member of the nicastrin family of proteins. It is a component of the aspartyl protease γ-secretase complex and serves to stabilize and direct γ-secretase components to proper positions in the plasma membrane. The γ-secretase complex mediates the cleavage of intramembrane proteins such as notch-1 and APP. Mature human nicastrin is a 676 amino acid type I transmembrane glycoprotein. It contains a 636 aa extracellular domain (aa 34 - 669) that shows a 58 aa sequence (aa 312 - 369) which interacts with γ-secretase substrates. There are multiple splice variants of nicastrin. Over aa 34 - 669, human nicastrin shares 90% aa identity with mouse nicastrin.
| Reactivity: | Human |
| Details: | Sheep IgG Polyclonal |
| Applications: | WB, IHC |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #716918 |
| Applications: | ICC |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ELISA, ICC/IF |
![Western Blot: Nicastrin AntibodyBSA Free [NBP1-77269]](https://resources.bio-techne.com/images/products/Nicastrin-Antibody-Western-Blot-NBP1-77269-img0002.jpg "Western Blot: Nicastrin AntibodyBSA Free [NBP1-77269]")
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #716910 |
| Applications: | WB |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ELISA, ICC/IF |
![Western Blot: Nicastrin AntibodyBSA Free [NBP1-77270]](https://resources.bio-techne.com/images/products/Nicastrin-Antibody-Western-Blot-NBP1-77270-img0002.jpg "Western Blot: Nicastrin AntibodyBSA Free [NBP1-77270]")
| Reactivity: | Human |
| Details: | Sheep IgG Polyclonal |
| Applications: | WB |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #019 |
| Applications: | WB, IP |
![Western Blot: Nicastrin Antibody (019) [NBP2-89828]](https://resources.bio-techne.com/images/products/Nicastrin-Antibody-019-Western-Blot-NBP2-89828-img0001.jpg "Western Blot: Nicastrin Antibody (019) [NBP2-89828]")
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #004 |
| Applications: | ICC/IF |
![Immunocytochemistry/ Immunofluorescence: Nicastrin Antibody (004) [NBP2-89826]](https://resources.bio-techne.com/images/products/Nicastrin-Antibody-004-Immunocytochemistry-Immunofluorescence-NBP2-89826-img0001.jpg "Immunocytochemistry/ Immunofluorescence: Nicastrin Antibody (004) [NBP2-89826]")
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ICC/IF |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #002 |
| Applications: | Flow |
![Flow Cytometry: Nicastrin Antibody (002) [NBP2-89825]](https://resources.bio-techne.com/images/products/Nicastrin-Antibody-002-Flow-Cytometry-NBP2-89825-img0001.jpg "Flow Cytometry: Nicastrin Antibody (002) [NBP2-89825]")
| Applications: | WB, ELISA, MA, AP |
| Applications: | WB, ELISA, MA, AP |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | ICC/IF |
![Immunocytochemistry/ Immunofluorescence: Nicastrin Antibody [NBP2-57365]](https://resources.bio-techne.com/images/products/Nicastrin-Antibody-Immunocytochemistry-Immunofluorescence-NBP2-57365-img0001.jpg "Immunocytochemistry/ Immunofluorescence: Nicastrin Antibody [NBP2-57365]")
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #004 |
| Applications: | ICC/IF |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #002 |
| Applications: | Flow |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #019 |
| Applications: | WB, IP |
| Applications: | WB |
![Western Blot: Nicastrin Overexpression Lysate [NBP2-10287]](https://resources.bio-techne.com/images/products/Nicastrin-Overexpression-Lysate-Adult-Normal-Western-Blot-NBP2-10287-img0001.jpg "Western Blot: Nicastrin Overexpression Lysate [NBP2-10287]")
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC |
![Immunohistochemistry: Nicastrin Antibody [NBP2-38741]](https://resources.bio-techne.com/images/products/Nicastrin-Antibody-Immunohistochemistry-NBP2-38741-img0001.jpg "Immunohistochemistry: Nicastrin Antibody [NBP2-38741]")
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, IP |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ELISA, ICC/IF |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ELISA, ICC/IF |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ELISA, ICC/IF |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ELISA, ICC/IF |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ELISA, ICC/IF |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ELISA, ICC/IF |