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P-Selectin/CD62P Products

P-Selectin, also known as CD62P, GMP-140, PADGEM, and LECAM-3, is a transmembrane adhesion protein that is upregulated on activated platelets and vascular endothelial cells. It binds to hematopoietic cell PSGL-1/CD162 with highly clustered O-linked sialyl Lewis-x (sLex) tetrasaccharides and sulfated tyrosine, as well as to heparin sulfate, Versican, and CD42b/GPIb alpha. P-Selectin mediates the initial interaction of circulating leukocytes with activated endothelial cells that produce a characteristic ‘rolling’ of the leukocytes on the endothelium. It is therefore critical for leukocyte extravasation at sites of inflammation and leukocyte involvement in thrombus formation at sites of vascular injury.

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317 results for "P-Selectin/CD62P" in Products

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317 results for "P-Selectin/CD62P" in Products

P-Selectin/CD62P Products

P-Selectin, also known as CD62P, GMP-140, PADGEM, and LECAM-3, is a transmembrane adhesion protein that is upregulated on activated platelets and vascular endothelial cells. It binds to hematopoietic cell PSGL-1/CD162 with highly clustered O-linked sialyl Lewis-x (sLex) tetrasaccharides and sulfated tyrosine, as well as to heparin sulfate, Versican, and CD42b/GPIb alpha. P-Selectin mediates the initial interaction of circulating leukocytes with activated endothelial cells that produce a characteristic ‘rolling’ of the leukocytes on the endothelium. It is therefore critical for leukocyte extravasation at sites of inflammation and leukocyte involvement in thrombus formation at sites of vascular injury.

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Applications: WB, Simple Western, IHC
Reactivity: Mouse, Rat
Applications: IHC, Flow, IP
Reactivity: Human, Mouse, Equine
Applications: WB, Simple Western, AdBlk
Reactivity: Human, Rat
Applications: Simple Plex

Simple Plex Human P-Selectin assay kit for use on Ella instrument. Contains cartridge, sample diluent SD13, and wash buffer.

Applications: IHC, AdBlk
Reactivity: Human
Applications: Flow
Reactivity: Human
Applications: WB
Reactivity: Mouse
Applications: WB, AdBlk
Reactivity: Human
Applications: Simple Plex

Simple Plex Non-Human Primate P-Selectin assay kit for use on Ella instrument. Contains cartridge, sample diluent SD13, and wash buffer.

Applications: WB
Reactivity: Mouse
Applications: WB
Reactivity: Human
Applications: Simple Plex

Control for use with Human and Non-Human Primate P-Selectin/CD62P Simple Plex Assay Cartridge Kit

Applications: IHC, WB
Reactivity: Human
Catalog #: NBP1-50764
Applications: IHC, WB
Reactivity: Human, Mouse, Rat
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