Pappalysin-2/PAPP-A2 Products
Pappalysins comprise one of the five families of Metzincins (other families include ADAMs/ADAMTSs, MMPs, Astacins, and Serralysins). Pappalysin-1 (PAPP-A) is an important pregnancy protein and increases in plasma by a factor of about 150 during pregnancy. Reduced maternal serum PAPP-A is a major marker of Down syndrome in the first trimester of pregnancy. PAPP-A cleaves IGFBP-4 and -5 (insulin-like growth factor-binding protein-4 and 5) at a single site, resulting in the release of bioactive IGF. Pappalysin-2 (PAPP-A2; also called PAPP-E) shares 45% amino acid identity with PAPP-A and cleaves IGFBP-2.
42 results for "Pappalysin-2/PAPP-A2" in Products
42 results for "Pappalysin-2/PAPP-A2" in Products
Pappalysin-2/PAPP-A2 Products
Pappalysins comprise one of the five families of Metzincins (other families include ADAMs/ADAMTSs, MMPs, Astacins, and Serralysins). Pappalysin-1 (PAPP-A) is an important pregnancy protein and increases in plasma by a factor of about 150 during pregnancy. Reduced maternal serum PAPP-A is a major marker of Down syndrome in the first trimester of pregnancy. PAPP-A cleaves IGFBP-4 and -5 (insulin-like growth factor-binding protein-4 and 5) at a single site, resulting in the release of bioactive IGF. Pappalysin-2 (PAPP-A2; also called PAPP-E) shares 45% amino acid identity with PAPP-A and cleaves IGFBP-2.
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IP |
| Source: | NS0 |
| Accession #: | Q9BXP8 |
| Applications: | EnzAct |
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #242011 |
| Applications: | WB, IP |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ELISA, ICC/IF |
![Western Blot: Pappalysin-2/PAPP-A2 AntibodyBSA Free [NBP1-76487]](https://resources.bio-techne.com/images/products/Pappalysin-2-PAPP-A2-Antibody-Western-Blot-NBP1-76487-img0001.jpg "Western Blot: Pappalysin-2/PAPP-A2 AntibodyBSA Free [NBP1-76487]")
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC |
![Immunohistochemistry-Paraffin: Pappalysin-2/PAPP-A2 Antibody [NBP1-87339]](https://resources.bio-techne.com/images/products/Pappalysin-2-PAPP-A2-Antibody-Immunohistochemistry-Paraffin-NBP1-87339-img0010.jpg "Immunohistochemistry-Paraffin: Pappalysin-2/PAPP-A2 Antibody [NBP1-87339]")
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC |
![Immunohistochemistry-Paraffin: Pappalysin-2/PAPP-A2 Antibody [NBP1-87340]](https://resources.bio-techne.com/images/products/Pappalysin-2-PAPP-A2-Antibody-Immunohistochemistry-Paraffin-NBP1-87340-img0010.jpg "Immunohistochemistry-Paraffin: Pappalysin-2/PAPP-A2 Antibody [NBP1-87340]")
| Applications: | ELISA |
| Applications: | ELISA |
| Applications: | AC |
| Applications: | AC |
| Applications: | AC |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ELISA, ICC/IF |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ELISA, ICC/IF |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ELISA, ICC/IF |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ELISA, ICC/IF |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ELISA, ICC/IF |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ELISA, ICC/IF |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ELISA, ICC/IF |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ELISA, ICC/IF |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ELISA, ICC/IF |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ELISA, ICC/IF |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ELISA, ICC/IF |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ELISA, ICC/IF |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ELISA, ICC/IF |