PDGF R alpha Products
PDGF R alpha (Platelet-Derived Growth Factor Receptor alpha) is a transmembrane receptor tyrosine kinase that can form homodimers or heterodimers with PDGF R beta when engaged by dimers of the PDGF ligands. PDGF R alpha binds to PDGF-AA, PDGF-AB, and PDGF-CC. It is strongly expressed in oligodendrocyte, lung, skin, and intestinal progenitor cells, at low levels in most mesenchymal cells, and can be induced by inflammation. PDGF R alpha function is important during formation of the cranial and cardiac neural crest, retina, gonads, lung alveoli, intestinal villi, skin, hair follicles, skeleton, teeth, palate, and interstitial kidney mesenchyme. Dysregulated PDGF R alpha signaling can result in spina bifida or cleft palate-type malformations. Postnatally, PDGF R alpha is implicated in gliomas and fibrotic disorders of lung, heart, and skin (scleroderma).
133 results for "PDGF R alpha" in Products
133 results for "PDGF R alpha" in Products
PDGF R alpha Products
PDGF R alpha (Platelet-Derived Growth Factor Receptor alpha) is a transmembrane receptor tyrosine kinase that can form homodimers or heterodimers with PDGF R beta when engaged by dimers of the PDGF ligands. PDGF R alpha binds to PDGF-AA, PDGF-AB, and PDGF-CC. It is strongly expressed in oligodendrocyte, lung, skin, and intestinal progenitor cells, at low levels in most mesenchymal cells, and can be induced by inflammation. PDGF R alpha function is important during formation of the cranial and cardiac neural crest, retina, gonads, lung alveoli, intestinal villi, skin, hair follicles, skeleton, teeth, palate, and interstitial kidney mesenchyme. Dysregulated PDGF R alpha signaling can result in spina bifida or cleft palate-type malformations. Postnatally, PDGF R alpha is implicated in gliomas and fibrotic disorders of lung, heart, and skin (scleroderma).
Reactivity: | Mouse |
Details: | Goat IgG Polyclonal |
Applications: | WB, Flow, IHC, Neut |
Source: | NS0 |
Accession #: | P26618.3 |
Applications: | BA |
Reactivity: | Mouse |
Details: | Goat IgG Polyclonal |
Applications: | Flow |
Reactivity: | Mouse |
Details: | Goat IgG Polyclonal |
Applications: | WB, IHC |
Reactivity: | Mouse |
Details: | Goat IgG Polyclonal |
Applications: | Flow |
Reactivity: | Mouse |
Details: | Goat IgG Polyclonal |
Applications: | Flow |
Reactivity: | Mouse |
Details: | Rat IgG2a Monoclonal Clone #189208 |
Applications: | WB |
Recombinant Monoclonal Antibody.
Reactivity: | Human, Mouse, Rat |
Details: | Rabbit IgG Monoclonal Clone #JF104-6 |
Applications: | IHC, WB, ICC/IF, Flow |
Reactivity: | Human, Mouse, Rat |
Details: | Mouse IgG1 Monoclonal Clone #OTI1C10 |
Applications: | IHC, WB |
Reactivity: | Human, Mouse |
Details: | Rat IgG2a Kappa Monoclonal Clone #APA5 |
Applications: | IHC, WB, Flow |
Recombinant Monoclonal
Reactivity: | Human, Mouse |
Details: | Rabbit Monoclonal Clone #BLR128H |
Applications: | WB, ICC/IF, IP |
Reactivity: | Mouse |
Details: | Rat IgG2 Monoclonal Clone #RM0004-3G28 |
Applications: | IHC, WB |
Recombinant Monoclonal Antibody
Reactivity: | Human, Mouse, Rat |
Details: | Rabbit IgG Monoclonal Clone #S06-6D3 |
Applications: | WB |
Reactivity: | Human, Mouse |
Details: | Rat IgG2a Kappa Monoclonal Clone #APA5 |
Applications: | IHC, WB, Flow |
Reactivity: | Human, Mouse, Rat |
Details: | Mouse IgG1 Monoclonal Clone #OTI1C10 |
Applications: | WB |
Reactivity: | Human, Mouse, Rat |
Details: | Mouse IgG1 Monoclonal Clone #OTI1C10 |
Applications: | WB |
Reactivity: | Human, Mouse, Rat |
Details: | Mouse IgG1 Monoclonal Clone #OTI1C10 |
Applications: | WB |
Reactivity: | Human, Mouse, Rat |
Details: | Mouse IgG1 Monoclonal Clone #OTI1C10 |
Applications: | WB |
Reactivity: | Human, Mouse, Rat |
Details: | Mouse IgG1 Monoclonal Clone #OTI1C10 |
Applications: | WB |
Reactivity: | Mouse |
Details: | Rat IgG2A Monoclonal Clone #189208 |
Applications: | WB |
Reactivity: | Mouse |
Details: | Rat IgG2A Monoclonal Clone #189208 |
Applications: | WB |
Reactivity: | Mouse |
Details: | Rat IgG2 Monoclonal Clone #RM0004-3G28 |
Applications: | IHC, WB |
Reactivity: | Mouse |
Details: | Rat IgG2 Monoclonal Clone #RM0004-3G28 |
Applications: | IHC, WB |
Reactivity: | Mouse |
Details: | Rat IgG2 Monoclonal Clone #RM0004-3G28 |
Applications: | IHC, WB |