PERK Products
PERK, a type 1 endoplasmic reticulum (ER) membrane kinase, mediates eIF2 alpha phosphorylation at Ser51 during the UPR (unfolded protein response). Protein synthesis is inhibited, thereby reducing the burden of protein substrate for the ER folding and degradation mechanism. Phosphorylation of eIF2 alpha by PERK also selectively promotes the expr...
14 results for "PERK" in Products
14 results for "PERK" in Products
PERK Products
PERK, a type 1 endoplasmic reticulum (ER) membrane kinase, mediates eIF2 alpha phosphorylation at Ser51 during the UPR (unfolded protein response). Protein synthesis is inhibited, thereby reducing the burden of protein substrate for the ER folding and degradation mechanism. Phosphorylation of eIF2 alpha by PERK also selectively promotes the expr...
Potent and selective PERK inhibitor; orally bioavailable
| Chemical Name: | 4-[2-Amino-4-methyl-3-(2-methyl-6-quinolinyl)benzoyl]-1,2-dihydro-1-methyl-2,5-diphenyl-3H-pyrazol-3-one hydrochloride |
| Purity: | ≥98% (HPLC) |
| Reactivity: | Human, Chicken, Avian - Chicken |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF |
![Immunohistochemistry-Paraffin: PERK Antibody [NBP1-80930]](https://resources.bio-techne.com/images/products/PERK-Antibody-Immunohistochemistry-Paraffin-NBP1-80930-img0010.jpg "Immunohistochemistry-Paraffin: PERK Antibody [NBP1-80930]")
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, KO |
| Reactivity: | Mouse |
| Details: | Rabbit Serum Polyclonal |
| Applications: | IHC, WB, ELISA, ICC/IF, IP, +1 More |
![Western Blot: PERK Antibody [NBP1-78017]](https://resources.bio-techne.com/images/products/PERK "Western Blot: PERK Antibody [NBP1-78017]")
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #5G5 |
| Applications: | WB, ELISA |
![Western Blot: PERK Antibody (5G5)BSA Free [NBP1-51661]](https://resources.bio-techne.com/images/products/PERK-Antibody-5G5-Western-Blot-NBP1-51661-img0001.jpg "Western Blot: PERK Antibody (5G5)BSA Free [NBP1-51661]")