PRAS40 Products
PRAS40 (40 kDa proline-rich Akt1 substrate), also known as AKT1S1, is a widely expressed component of the cytoplasmic mTOR complex (mTORC1). In response to insulin stimulation, Akt1 phosphorylation of PRAS40 relieves the basal PRAS40-mediated inhibition of mTORC1. Activated mTORC1 is a key effector of the cell survival pathway. PRAS40 phosphorylation by Akt3 or Pim1 similarly exerts an anti-apoptotic effect during tumor progression and neuronal ischemia . Alternate splicing generates an isoform that lacks the N-terminal 130 amino acids.
49 results for "PRAS40" in Products
49 results for "PRAS40" in Products
PRAS40 Products
PRAS40 (40 kDa proline-rich Akt1 substrate), also known as AKT1S1, is a widely expressed component of the cytoplasmic mTOR complex (mTORC1). In response to insulin stimulation, Akt1 phosphorylation of PRAS40 relieves the basal PRAS40-mediated inhibition of mTORC1. Activated mTORC1 is a key effector of the cell survival pathway. PRAS40 phosphorylation by Akt3 or Pim1 similarly exerts an anti-apoptotic effect during tumor progression and neuronal ischemia . Alternate splicing generates an isoform that lacks the N-terminal 130 amino acids.
| Reactivity: | Human, Mouse |
| Details: | Mouse IgG2a Monoclonal Clone #760502 |
| Applications: | WB, ICC |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #660928 |
| Applications: | WB, Simple Western, ICC |
| Reactivity: | Human |
| Details: | Sheep IgG Polyclonal |
| Applications: | IHC |
Recombinant Monoclonal Antibody.
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #1211A |
| Applications: | WB |
Recombinant Monoclonal Antibody
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #JE30-60 |
| Applications: | IHC, WB, ICC/IF, Flow |
Recombinant Monoclonal Antibody
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Monoclonal Clone #SR1679 |
| Applications: | IHC, WB, Flow, IP |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ELISA, ICC/IF |
![Western Blot: PRAS40 AntibodyBSA Free [NBP2-41221]](https://resources.bio-techne.com/images/products/PRAS40-Antibody-Western-Blot-NBP2-41221-img0001.jpg "Western Blot: PRAS40 AntibodyBSA Free [NBP2-41221]")
Recombinant Monoclonal Antibody
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #SR1680 |
| Applications: | WB, IP |
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB |
![Western Blot: PRAS40 Antibody [NBP2-19924]](https://resources.bio-techne.com/images/products/PRAS40-Antibody-Western-Blot-NBP2-19924-img0007.jpg "Western Blot: PRAS40 Antibody [NBP2-19924]")
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB |
![Western Blot: PRAS40 Antibody [NBP1-55261]](https://resources.bio-techne.com/images/products/PRAS40-Antibody-Western-Blot-NBP1-55261-img0004.jpg "Western Blot: PRAS40 Antibody [NBP1-55261]")
Recombinant Monoclonal Antibody
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #JE53-94 |
| Applications: | WB |
![PRAS40 [p Thr246] Antibody (JE53-94)](https://resources.bio-techne.com/images/products/nbp3-32790_rabbit-pras40-p-thr246-mab-je53-94-288202412442948.jpg "Western Blot: PRAS40 [p Thr246] Antibody (JE53-94) [NBP3-32790]")
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB |
![Western Blot: PRAS40 [p Ser183] Antibody [NBP3-13077]](https://resources.bio-techne.com/images/products/PRAS40-[p-Ser183]-Antibody-Western-Blot-NBP3-13077-img0001.jpg "Western Blot: PRAS40 [p Ser183] Antibody [NBP3-13077]")
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC |
![PRAS40 Antibody Immunohistochemistry-Paraffin: PRAS40 Antibody [NBP3-25066]](https://resources.bio-techne.com/images/products/nbp3-25066_rabbit-pras40-pab-201220231502645.jpg "Immunohistochemistry-Paraffin: PRAS40 Antibody [NBP3-25066]")
Recombinant Monoclonal Antibody
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Monoclonal Clone #2Y8Y3 |
| Applications: | WB |
![Western Blot: PRAS40 Antibody (2Y8Y3) [NBP3-16179]](https://resources.bio-techne.com/images/products/PRAS40-Antibody-2Y8Y3-Western-Blot-NBP3-16179-img0001.jpg "Western Blot: PRAS40 Antibody (2Y8Y3) [NBP3-16179]")
| Applications: | AC |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | ICC/IF |
![Immunocytochemistry/ Immunofluorescence: PRAS40 Antibody [NBP2-54956]](https://resources.bio-techne.com/images/products/PRAS40-Antibody-Immunocytochemistry-Immunofluorescence-NBP2-54956-img0001.jpg "Immunocytochemistry/ Immunofluorescence: PRAS40 Antibody [NBP2-54956]")
| Reactivity: | Drosophila |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB |
![Western Blot: PRAS40 [p Thr356] Antibody [NBP2-60783]](https://resources.bio-techne.com/images/products/PRAS40-[p-Thr356]-Antibody-Western-Blot-NBP2-60783-img0001.jpg "Western Blot: PRAS40 [p Thr356] Antibody [NBP2-60783]")
| Applications: | WB |
![Western Blot: PRAS40 Overexpression Lysate [NBP2-06037]](https://resources.bio-techne.com/images/products/PRAS40-Overexpression-Lysate-Adult-Normal-Western-Blot-NBP2-06037-img0001.jpg "Western Blot: PRAS40 Overexpression Lysate [NBP2-06037]")
| Applications: | WB |
![Western Blot: PRAS40 Overexpression Lysate [NBP2-10916]](https://resources.bio-techne.com/images/products/PRAS40-Overexpression-Lysate-Adult-Normal-Western-Blot-NBP2-10916-img0001.jpg "Western Blot: PRAS40 Overexpression Lysate [NBP2-10916]")
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC |
![Immunohistochemistry-Paraffin: PRAS40 Antibody [NBP2-57165]](https://resources.bio-techne.com/images/products/PRAS40-Antibody-Immunohistochemistry-Paraffin-NBP2-57165-img0001.jpg "Immunohistochemistry-Paraffin: PRAS40 Antibody [NBP2-57165]")
| Applications: | AC |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ELISA, ICC/IF |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ELISA, ICC/IF |
Contains 4 sets of 2 membranes - each spotted in duplicate with antibodies against 37 different kinases and 2 related total proteins
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ELISA, ICC/IF |