Proprotein Convertase 9/PCSK9 Products
PCSK9 (Proprotein Convertase 9, is a serine endoprotease that is highly expressed in the liver, intestine, and kidney. PCSK9 promotes the degradation of low density lipoprotein receptor (LDLR) by inducing receptor degradation in the lysosome following its internalization. PCSK9 regulates the amounts of LDLR in the circulation and hence, modulates cholesterol levels. Nonsense or loss-of-function mutations in PCSK9 are associated with decreased plasma LDL cholesterol levels.
8 results for "Proprotein Convertase 9/PCSK9" in Products
8 results for "Proprotein Convertase 9/PCSK9" in Products
Proprotein Convertase 9/PCSK9 Products
PCSK9 (Proprotein Convertase 9, is a serine endoprotease that is highly expressed in the liver, intestine, and kidney. PCSK9 promotes the degradation of low density lipoprotein receptor (LDLR) by inducing receptor degradation in the lysosome following its internalization. PCSK9 regulates the amounts of LDLR in the circulation and hence, modulates cholesterol levels. Nonsense or loss-of-function mutations in PCSK9 are associated with decreased plasma LDL cholesterol levels.
| Sensitivity: | 21.9 pg/mL |
| Applications: | ELISA |
| Assay Range: | 62.5 - 4,000 pg/mL (Cell Culture Supernates, Cell Lysates, Serum, EDTA Plasma, Heparin Plasma) |
| Assay Range: | 125 - 8,000 pg/mL |
| Applications: | ELISA |
| Reactivity: | Human, Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF, ELISA, ChIP |
![Western Blot: Proprotein Convertase 9/PCSK9 Antibody [NB300-959]](https://resources.bio-techne.com/images/products/Proprotein-Convertase-9-PCSK9-Antibody-Western-Blot-NB300-959-img0005.jpg "Western Blot: Proprotein Convertase 9/PCSK9 Antibody [NB300-959]")
| Source: | NS0 |
| Accession #: | Q8NBP7 |
| Applications: | BA |
| Assay Range: | 31.2 - 2,000 pg/mL |
| Applications: | ELISA |
| Reactivity: | Mouse, Rat |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Sheep IgG Polyclonal |
| Applications: | WB, ELISA, IP |
| Reactivity: | Human |
| Details: | Rat IgG2b Monoclonal Clone #499911 |
| Applications: | WB, IP |