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PTEN Products

The tumor suppressor gene PTEN (phosphatase and tensin homolog deleted on chromosome 10), also known as MMAC1 (mutated in multiple advanced cancers 1), encodes a phosphatase that contains the catalytic signature motif (HCXXGXXRS/T) found in all members of the protein tyrosine phosphatase family. In vitro, the recombinant PTEN has both lipid phosphatase and protein phosphatase activities. In vivo, the importance of PTEN catalytic activity in its tumor suppressor functions is underscored by the fact that the majority of PTEN missense mutations detected in tumor specimens target the phosphatase domain and cause a loss in PTEN phosphatase activity.

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128 results for "PTEN" in Products

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128 results for "PTEN" in Products

PTEN Products

The tumor suppressor gene PTEN (phosphatase and tensin homolog deleted on chromosome 10), also known as MMAC1 (mutated in multiple advanced cancers 1), encodes a phosphatase that contains the catalytic signature motif (HCXXGXXRS/T) found in all members of the protein tyrosine phosphatase family. In vitro, the recombinant PTEN has both lipid phosphatase and protein phosphatase activities. In vivo, the importance of PTEN catalytic activity in its tumor suppressor functions is underscored by the fact that the majority of PTEN missense mutations detected in tumor specimens target the phosphatase domain and cause a loss in PTEN phosphatase activity.

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Applications: ICC, KO
Reactivity: Human
Applications: WB, Simple Western, IHC, CyTOF-ready, ICFlow, KO
Reactivity: Human, Mouse, Rat
Applications: WB, IHC, CyTOF-ready, ICFlow, KO
Reactivity: Human, Mouse
Applications: WB
Reactivity: Human, Mouse, Rat
Applications: IHC, ICC
Reactivity: Human
Applications: WB, ICFlow, KO
Reactivity: Human, Mouse

Recombinant Monoclonal Antibody.

Applications: IHC, WB, ICC/IF, IP, KO
Reactivity: Human, Mouse, Rat

Recombinant Monoclonal Antibody

Applications: ICFlow
Reactivity: Human, Mouse, Rat
Applications: ICFlow
Reactivity: Human
Applications: InhibAct
Applications: ICFlow
Reactivity: Human
Applications: ICFlow
Reactivity: Human
Applications: ICFlow
Reactivity: Human, Mouse

Recombinant Monoclonal Antibody.

Applications: ICFlow
Reactivity: Human
Applications: ICFlow
Reactivity: Human
Applications: ICFlow
Reactivity: Human, Mouse

Recombinant Monoclonal Antibody.

Applications: ICFlow
Reactivity: Human, Mouse

Recombinant Monoclonal Antibody.

Applications: ICFlow
Reactivity: Human
Applications: ICFlow
Reactivity: Human, Mouse

Recombinant Monoclonal Antibody.

Applications: ICFlow
Reactivity: Human, Mouse, Rat
Applications: ICFlow
Reactivity: Human, Mouse, Rat
Applications: ICFlow
Reactivity: Human, Mouse, Rat
Applications: IHC, WB, IP
Reactivity: Human, Mouse
Applications: IHC, WB
Reactivity: Human
Applications: IHC, WB
Reactivity: Human
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