PYK2/FAK2 Products
FAK (Focal Adhesion Kinase) is a non-receptor protein tyrosine kinase involved in signal transduction from integrin-enriched focal adhesion sites that mediate cell contact with the extracellular matrix. FAK-enhanced signals have been shown to mediate the survival of anchorage-dependent cells and are critical for efficient cell migration in response to growth factor receptor and integrin stimulation. Elevated expression of FAK in human tumors has been correlated with increased malignancy and invasiveness.
7 results for "PYK2/FAK2" in Products
7 results for "PYK2/FAK2" in Products
PYK2/FAK2 Products
FAK (Focal Adhesion Kinase) is a non-receptor protein tyrosine kinase involved in signal transduction from integrin-enriched focal adhesion sites that mediate cell contact with the extracellular matrix. FAK-enhanced signals have been shown to mediate the survival of anchorage-dependent cells and are critical for efficient cell migration in response to growth factor receptor and integrin stimulation. Elevated expression of FAK in human tumors has been correlated with increased malignancy and invasiveness.
| Reactivity: | Human |
| Details: | Sheep IgG Polyclonal |
| Applications: | WB, IHC |
| Reactivity: | Human |
| Details: | Mouse IgG2b Kappa Monoclonal Clone #1F9 |
| Applications: | WB, ELISA, IP |
![Western Blot: PYK2/FAK2 Antibody (1F9) [H00002185-M01]](https://resources.bio-techne.com/images/products/PYK2-FAK2-Antibody-1F9-Western-Blot-H00002185-M01-img0008.jpg "Western Blot: PYK2/FAK2 Antibody (1F9) [H00002185-M01]")
| Reactivity: | Human |
| Details: | Mouse IgG2a Kappa Monoclonal Clone #X1 |
| Applications: | WB, ELISA |
![Western Blot: PYK2/FAK2 Antibody (X1) [H00002185-M03]](https://resources.bio-techne.com/images/products/PYK2-FAK2-Antibody-X1-Western-Blot-H00002185-M03-img0002.jpg "Western Blot: PYK2/FAK2 Antibody (X1) [H00002185-M03]")
| Applications: | WB |
![Western Blot: PYK2/FAK2 Overexpression Lysate [NBP2-04265]](https://resources.bio-techne.com/images/products/PYK2-Overexpression-Lysate-Adult-Normal-Western-Blot-NBP2-04265-img0001.jpg "Western Blot: PYK2/FAK2 Overexpression Lysate [NBP2-04265]")
Contains 4 sets of 2 membranes - each spotted in duplicate with antibodies against 37 different kinases and 2 related total proteins
Potent VEGFR, PDGFRβ and KIT inhibitor
| Alternate Names: | SU 11248 |
| Chemical Name: | N-[2-(Diethylamino)ethyl]-5-[(Z)-(5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidine)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide (2S)-2-hydroxybutanedioate salt |
| Purity: | ≥99% (HPLC) |
